Laryngeal rhabdomyoma in a golden retriever

Abstract

A three-year-old male golden retriever had had progressive dyspnoea, exercise intolerance, stridor, and a modified bark for five months. A mass 2 cm in diameter was present dorsal to the right side of the larynx. Histological examination revealed cross-striations in some elongated cells, consistent with a diagnosis of rhabdomyoma, a diagnosis which was confirmed by positive immunohistochemical staining for myoglobin and desmin. The mass could not be removed without total laryngectomy and a permanent tracheostomy and the dog was euthanased.

A laryngeal rhabdomyosarcoma in a dog

“…Direct inspection by laryngoscopy under general anaesthesia can confirm the presence of a mass and may allow tissue sample for histology. CT scanner can help to accurately determine the margins of the lesion and to direct the choice towards the surgical procedure to be implemented (Clercx and others 1998). …”

“…Few cases have been described in the literature (Clercx and others 1998, Dunbar and others 2012, Caserto 2013). RMS has a moderate metastatic rate, but can spread to the lungs, liver, spleen, kidneys and adrenal glands.…”

Laryngopharyngeal Mass in a Dog with Upper Airway Obstruction

“…The majority of rhabdomyomas in domestic animals are congenital and associated with the heart 5 . The primary site for extracardiac rhabdomyomas in mature animals is the larynx; however, these tumors are extremely rare and only 7 have been reported in the literature 2,6,7 . Although location often prevents complete surgical excision, laryngeal rhabdomyomas are benign and typically appear as slowly growing solitary nodules.…”

Cartilaginous Tumors of the Larynx and Trachea in the Dog

“…13 Managing patients after total laryngectomy is difficult because of the requisite permanent tracheostomy. 10 The prognosis should be guarded for those patients with large laryngeal tumors. Tracheal chondromas and osteochondromas may be amenable to complete resection.…”

“…29,31 The most common types of primary laryngeal tumors are squamous cell carcinoma, oncocytoma, and rhabdomyoma. 7,10,26,31 Mast cell tumor, 7,15,31 melanoma, 22,31 undifferentiated carcinoma, 7 leiomyoma, 20 rhabdomyosarcoma, 17 lipoma, 29 plasmacytoma, 16 granular cell tumor, 28 and osteosarcoma 5 have also been reported. Primary tracheal neoplasia is even more uncommon.…”