Laryngeal neurofibroma: case report of a child

Chen, Yu‐Chun; Lee, Kuo‐Sheng; Yang, Chang‐Hsien; Chang, Ke-Chang

doi:10.1016/s0165-5876(02)00151-9

Cited by 16 publications

(11 citation statements)

References 9 publications

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“…La vía de abordaje dependerá del tamaño y de la extensión del tumor; se prefiere la vía endoscópica para tumores pequeños y el abordaje abierto en tumores más grandes. 2 De los 72 casos de NFL, el 30,5 % fueron resecados por vía endoscópica, incluido este caso. Es de destacar que hasta el año 1990, que se realiza la primera resección endoscópica, la vía de abordaje de elección era la externa, ya sea por tirotomía o faringotomía lateral.…”

Section: Discussionunclassified

“…La localización laríngea es muy infrecuente 1 y afecta principalmente a la supraglotis, con mayor frecuencia a los repliegues aritenoepiglóticos y/o aritenoides. 2 En la mayoría de los casos, se encuentran asociados a la neurofibromatosis tipo 1 o 2 (esta última con menor frecuencia), pero también pueden ocurrir de forma aislada. 3 La neurofibromatosis tipo 1 (NF1) es una enfermedad autosómica dominante, neurocutánea y sistémica.…”

Section: Introductionunclassified

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Neurofibromatosis laríngea pediátrica: reporte de localización atípica

2023

Arch Argent Pediat

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Los neurofibromas laríngeos (NFL) son tumores benignos poco frecuentes de localización principalmente supraglótica. Se manifiestan con síntomas obstructivos de la vía aérea. El tratamiento es la resección completa del tumor mediante abordaje endoscópico; se reserva la cirugía abierta para tumores de gran extensión.Se presenta el caso de un paciente pediátrico con localización atípica de NFL asociado a neurofibromatosis tipo 1 (NF1). Se realizó resección endoscópica del tumor y la anatomía patológica informó neurofibroma plexiforme. Es importante sospechar de esta patología en todo niño con estridor inspiratorio atípico progresivo. Se sugiere seguimiento a largo plazo por la alta probabilidad de recidiva.

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Section: Discussionunclassified

Section: Introductionunclassified

Neurofibromatosis laríngea pediátrica: reporte de localización atípica

2023

Arch Argent Pediat

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“…They are locally infiltrating and complete resection is considered difficult. 7 The usual site of occurrence of a laryngeal neurofibroma is the supraglottis; probable cause being the abundance of terminal nerve plexuses of the superior laryngeal nerve. 8 These tumors are usually seen as large, smooth, submucosal masses located in the supraglottis resulting in difficulty in breathing and swallowing.…”

Section: Declarationmentioning

confidence: 99%

Plexiform Neurofibroma of the Larynx: A Challenging Management Dilemma

Kapre¹

2013

International Journal of Phonosurgery &Amp; Laryngology

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Introduction: Among the many causes responsible for stridor in the pediatric population, tumors of the larynx are relatively rare. Rarer still is the presence of endolaryngeal neurofibromas. Plexiform neurofibromas are associated with type I neurofibromatosis (NF1). Their typical characteristic is that they are diffuse tumors with indistinct margins, which makes complete resection a challenge and the chances of recurrences higher.Objective: To document our experience with endolaryngeal neurofibromas and to discuss the treatment options available for this rare condition. Methods:We present two cases of plexiform neurofibromas in pediatric patients. Both children presented with large supraglottic masses which interfered with breathing and swallowing. They also fulfilled the criteria for type I neurofibroma. Endolaryngeal approach with microdebrider and laser-assisted surgical excision was performed in both cases.Result: Following surgery, both patients had uneventful recovery and no subsequent breathing or swallowing difficulties. Conclusion:The dilemma in the management of endolaryngeal neurofibroma is the choice between endolaryngeal laser and aggressive external approach surgery. A short review of the limited existing literature shows that it is wiser to limit the surgery to as complete a resection as is possible endoscopically.

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“…9 Change or loss of voice in patients with NF1 has been associated with laryngeal and hypopharyngeal neurofibromas. [10][11][12][13] However, laryngeal involvement in NF1 is rare, and voice abnormalities have also been reported in absence of such tumors (Table 2). Hence, it is expected that NF1 patients (or at least some of them) will demonstrate dysphonic characteristics.…”

Section: Introductionmentioning

confidence: 99%