Laryngeal cancer mortality trends in European countries

Abstract

After a steady increase between the 1950s and the 1970s, laryngeal cancer mortality has been levelling off since the early 1980s in men from most western and southern European countries and since the early 1990s in central and eastern Europe. To update trends in laryngeal cancer mortality, we analyzed data provided by the World Health Organization over the last two decades for 34 European countries and the European Union (EU) as a whole. For major European countries, we also identified significant changes in trends between 1980 and 2012 using joinpoint regression analysis. Male mortality in the EU was approximately constant between 1980 and 1991 (annual percent change, APC=−0.5%) and declined by 3.3% per year in 1991–2012. EU age‐standardized (world population) rates were 4.7/100,000 in 1990–91 and 2.5/100,000 in 2010–2011. Rates declined in most European countries, particularly over the last two decades. In 2010–11, the highest male rates were in Hungary, the Republic of Moldova, and Romania (over 6/100,000), and the lowest ones in Finland, Norway, Sweden, and Switzerland (below 1/100,000). In EU women, mortality was stable around 0.29/100,000 between 1980 and 1994 and slightly decreased thereafter (APC=−1.3%; 0.23/100,000 in 2000–01). We also considered male incidence trends for nine European countries or cancer registration areas. In most of them, declines were observed over recent decades. Laryngeal cancer mortality thus showed favourable trends over the last few decades in most Europe, following favourable changes in tobacco and, mostly for Mediterranean countries, alcohol consumption.

Impact of stage, management and recurrence on survival rates in laryngeal cancer

“…Based on a review of the American National Cancer Data Base (NCDB), survival rates following diagnosis of LSCC in the United States seem to have decreased [1] but remain stable in other countries [2]. LSCC mortality varies widely between different European countries, with most Scandinavian countries having low rates [3,4]. In Norway, the estimated age-standardized mortality rate across patients of all ages and both sexes in 2012 was 0.4 per 100,000 for laryngeal cancer compared to 0.7 per 100,000 in the United States [5].…”

The frequency and characteristics of regional metastases and their impact on the survival of patients with T1 and T2 laryngeal cancer

“…[4,8] U zemljama u okruženju morbiditet je nepromenjen. [9] Od svih malignih bolesti 1% ine karcinomi larinksa. [10] Kako je najzna ajniji etiološki faktor u nastanku laringealnog karcinoma pušenje, karcinomi larinksa su eš i kod muška-raca, prevashodno zbog u estalije štetne puša ke navike.…”

Evidence and evidence gaps of laryngeal cancer surgery

“…In 2012, the age-standardized incidence of laryngeal cancer in European males amounted to 8.8 per 100,000; in the European Union it was 8.3 per 100,000 [8]. Based on the data of the World Health Organization, Chatenoud et al [9] analyzed the mortality rate of laryngeal cancer during the last two decades in 34 European countries and the whole European Union (EU). While the mortality of male patients was nearly constant between 1980 and 1991, a decline of the mortality of 3.3% per year could be found from 1991 to 2012.…”