Larvicidal efficacy of Andrographis paniculata and Tinospora cordifolia against aedes aegypti: A dengue vector

Paul, Anubrata; Raj, V. Samuel; Vibhuti, Arpana; Pandey, Ramendra Pati

doi:10.4103/pr.pr_35_20

Cited by 8 publications

(3 citation statements)

References 18 publications

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“…The extent to which L. donovani infection of domestic animals promotes transmission to other animals or humans in India is not recognized. Evidence from prior vector-borne disease eradication methods showed that domestic species' developing diseases hampered elimination [17,18,20,21,22,24,25]. public health and veterinary researchers have neglected the role that few animals role in the maintenance and transmission of VL, and that this aspect of the epizootiology of VL needs to be critically examined to update prevention and treatment programmes in kala-azar endemic areas.…”

Section: Resultsmentioning

confidence: 99%

A systematic assessment of Leishmania donovani infection in domestic and wild animal reservoir hosts of zoonotic Visceral Leishmaniasis

Pandey

2023

Preprint

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Background Leishmaniasis is a neglected disease with a global spread that affects both domestic and wild animals in addition to people. Leishmania donovani is the suspected anthroponotic cause of VL in India, where it is an endemic disease. The reservoir hosts play a crucial role in the life cycle of the Leishmania parasite. The complicated connection between the pathogen, vector, and reservoir exhibits geographical and temporal diversity. Human-to-human and, to a lesser extent, human-to-animal transmission is the principal mechanism for the maintenance of anthroponotic diseases. Scope and approach A deliberate, systematic search was conducted on PubMed, Science Direct, and Google Scholar using keywords such as "Leishmania donovani," "zoonotic visceral leishmaniasis," and "wild animal reservoir for leishmania donovani." 530 potentially significant references were obtained from these 507 were disallowed due to copy avoidance, irrelevant titles, research publications from nations other than India, or modified compositions. The remaining 20 investigations were later rejected because they did not meet the criteria for inclusion. Finally 3 research papers with 867 goats, 161 cattles, 106 chickens, 26 sheep, 3 buffaloes, 406 dogs and 309 rats were reported. Conclusion According to the review, goats are the epidemic's primary host and possible reservoir in several regions of India. In the endemic regions of the disease, some species of rodents along with the canines appear to be maintaining the L. donovani transmission cycle.

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Section: Resultsmentioning

confidence: 99%

A systematic assessment of Leishmania donovani infection in domestic and wild animal reservoir hosts of zoonotic Visceral Leishmaniasis

Pandey

2023

Preprint

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show abstract

“…The extent to which L. donovani infection of domestic animals promotes transmission to other animals or humans in is not recognized. Evidence from prior vector-borne disease eradication methods showed that domestic species' developing diseases hampered elimination [17,18,20,21,22]. public health and veterinary researchers have neglected the role that few animals role in the maintenance and transmission of VL, and that this aspect of the epizootiology of VL needs to be critically examined to update prevention and treatment programmes in kala-azar endemic areas.…”

Section: Resultsmentioning

confidence: 99%

A Systematic Assessment of <em>Leishmania donovani</em> Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis

Peer¹,

Priyadarshini²,

Gupta³

et al. 2023

Preprint

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Background: Leishmaniasis is a neglected disease with a global spread that affects both domestic and wild animals in addition to people. Leishmania donovani is the suspected anthroponotic cause of VL in India, where it is an endemic disease. The reservoir hosts play a crucial role in the life cycle of the Leishmania parasite. The complicated connection between the pathogen, vector, and reservoir exhibits geographical and temporal diversity. Human-to-human and, to a lesser extent, human-to-animal transmission is the principal mechanism for the maintenance of anthroponotic diseases. Scope and approach: A deliberate, systematic search was conducted on PubMed, Science Direct, and Google Scholar using keywords such as "Leishmania donovani," "zoonotic visceral leishmaniasis," and "wild animal reservoir for leishmania donovani." 530 potentially significant references were obtained from these 507 were disallowed due to copy avoidance, irrelevant titles, research publications from nations other than India, or modified compositions. The remaining 20 investigations were later rejected because they did not meet the criteria for inclusion. Finally 3 research papers with 867 goats, 161 cattles, 106 chickens, 26 sheep, 3 buffaloes, 406 dogs and 309 rats were reported. Conclusion: According to the review, goats are the epidemic's primary host and possible reservoir in several regions of India. In the endemic regions of the disease, some species of rodents along with the canines appear to be maintaining the L. donovani transmission cycle.

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“…The outcomes illustrate the utilization of therapeutically relevant radiation doses to facilitate concurrent receptor-mediated enhanced chemotherapeutic administration, while minimizing systemic toxicity. 92,105,106,107,108 .…”

Section: Micellesmentioning

confidence: 99%

Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery

Pandey,

Dhiman,

Bazad

et al. 2023

Preprint

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Breast cancer (BC) is one of the most common types of cancer in women. Triple-negative breast cancer (TNBC), characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), exhibits a highly aggressive phenotype with increased metastasis and resistance to conventional treatments. Nanocarrier technology is consistently employed to overcome limitations associated with traditional breast cancer therapy. The targeted drug delivery approach using nanocarriers enhances bioavailability, prolongs circulation, and facilitates effective drug accumulation at the tumor site through active or passive targeting. Currently, the FDA has approved a few nanocarrier systems, and numerous nano formulations are undergoing preclinical and clinical development for breast cancer targeting. Common nanocarrier types include polymeric micelles, microemulsions, magnetic microemulsions, liposomes, dendrimers, carbon nanotubes, and magnetic nanoparticles (NPs). This review extensively explores the targeting potential of nanocarriers in breast cancer. This study will provide a concise summary of current advances in treatment of breast cancer and diagnostics.

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Larvicidal efficacy of Andrographis paniculata and Tinospora cordifolia against aedes aegypti: A dengue vector

Cited by 8 publications

References 18 publications

A systematic assessment of Leishmania donovani infection in domestic and wild animal reservoir hosts of zoonotic Visceral Leishmaniasis

A systematic assessment of Leishmania donovani infection in domestic and wild animal reservoir hosts of zoonotic Visceral Leishmaniasis

A Systematic Assessment of <em>Leishmania donovani</em> Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis

Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug Delivery

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