Larvicidal Activity of Essential Oils Against Aedes aegypti (Diptera: Culicidae)

Abstract

: The Aedes aegypti is responsible for the transmission of arboviruses, which compromise public health. In the search for synthetic product alternatives, essential oils (OEs) have been highlighted by many researchers as natural insecticides. This systematic review (SR) was performed according to PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and had as it’s objective to evaluate studies addressing OEs with larvicidal properties against Ae. aegypti, through electronic database searches (Pubmed, Science Direct and Scielo), covering an overview of the plant sources OEs, which plant parts were used, the extraction methods, analytical techniques, major and/or secondary constituents with greater percentages, as well as the LC50s responsible for larval mortality. Following study analysis, plants distributed across 32 families, 90 genera and 175 species were identified. The Lamiaceae, Myrtaceae, Piperaceae, Asteraceae, Rutaceae, Euphorbiaceae and Lauraceae families obtained the highest number of species with toxic properties against larvae from this vector. Practically all plant parts were found to be used for OE extraction. Hydrodistillation and steam distillation were the main extraction methods identified, with GC-MS/GC-FID representing the main analytical techniques used to reveal their chemical composition, especially of terpene compounds. In this context, OEs are promising alternatives for the investigation of natural, ecologically correct and biodegradable insecticides with the potential to be used in Ae. aegypti control programs.

The essential oil ofSchinus terebinthifoliusand its nanoemulsion and isolated monoterpenes: investigation of their activity againstCulex pipienswith insights into the adverse effects on non‐target organisms

“…One approach is the application of plant-based products, particularly plant essential oils (EOs), where EOs have exhibited promising bioactivities against harmful insects, including mosquitoes. [6][7][8][9][10][11] In this regard, plant EOs seem more appropriate as pest control agents than chemical pesticides, even though the latter are more potent. Natural products, including EOs, are economically feasible, biodegrade to non-toxic metabolites, commonly have low toxicity towards beneficial non-target species, and exert their action through multiple mechanisms.…”

“…One approach is the application of plant‐based products, particularly plant essential oils (EOs), where EOs have exhibited promising bioactivities against harmful insects, including mosquitoes 6–11 . In this regard, plant EOs seem more appropriate as pest control agents than chemical pesticides, even though the latter are more potent.…”

Evaluation of the influence of calcium chloride on the behavior of phases of nanosystems applied in the larvicidal control of Aedes aegypti

“…aegypti, including dengue, Zika virus, wild yellow fever and Chikungunya (Santos et al, 2020). These arboviruses present a constant threat to human health, with the highest number of notifications being found in tropical and subtropical areas (Souza et al, 2020;Santana et al, 2021), where environmental impacts and climatic conditions of temperature and humidity allow the maintenance of the viral cycle (Fujiwara et al, 2017). Due to the high number of notifications, the Brazilian Ministry of Health has coordinated with the state and municipal health secretariats to carry out task forces in order to control the emergence of new cases (Maia et al, 2019).…”

“…In this scenario, the control of Ae. aegypti is presented as the main preventive measure to reduce the spread of these related arboviruses (Souza et al, 2020). For vector control, basically, three methodologies are used: physical or mechanical control, biological control and chemical control (Maia et al, 2019).…”

Bioactivity and safety evaluations of Cupressus sempervirens essential oil, its nanoemulsion and main terpenes against Culex quinquefasciatus Say

“…Thus, the chances of pests developing resistance to such materials are less likely (Isman 2015;Benelli and Pavela 2018a, b;Garay et al 2020). Undoubtedly, EOs and their bioactive components, especially monoterpenes, are good examples as biorational pest control options, as many of them have shown promising bioactivities against harmful insects, including mosquito vectors (Karr and Coats 1988;Benelli and Pavela 2018a, b;Benelli et al 2018;Bortolucci et al 2019;Hung et al 2020;de Souza et al 2020;Manh and Tuyet 2020;Lima et al 2021;Nakasen et al 2021;Felix et al 2021;Pavela et al 2021a, b). The genus Cupressus (Cupressaceae) includes plants that are widespread in North America, the Mediterranean Basin and the subtropical western part of Asia, including Saudi Arabia (Rguez et al 2018).…”