Largest giant left atrium in rheumatic heart disease

Pandit, Bhagya Narayan; Aggarwal, Priyanka; Subramaniyan, Siva; Gujral, Jaskaran Singh; Nath, Ranjit Kumar

doi:10.1016/j.jccase.2020.11.022

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…5 Métodos de imagem, como ressonância magnética cardíaca e tomografia computadorizada, podem ser necessários para uma avaliação mais precisa do tamanho do átrio esquerdo e de sua relação com as estruturas circunvizinhas. 6 Poucos casos de átrio esquerdo gigante são assintomáticos; quando sintomáticos, geralmente estão relacionados à valvopatia mitral ou à compressão do esôfago e das vias aéreas pelo aumento da parede posterior do átrio esquerdo, resultando em disfagia e disfunção respiratória. O aumento do átrio esquerdo também possibilita a formação de trombos, favorecendo a ocorrência de eventos tromboembólicos.…”

Section: Discussionunclassified

Átrio Esquerdo Gigante por Provável Doença Reumática e Insuficiência Mitral Funcional Atrial

Feitosa,

Andrade

2024

Arq Bras Cardiol: Imagem cardiovasc.

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Section: Discussionunclassified

Átrio Esquerdo Gigante por Provável Doença Reumática e Insuficiência Mitral Funcional Atrial

Feitosa,

Andrade

2024

Arq Bras Cardiol: Imagem cardiovasc.

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“…Patients with RHD, due to the persistent inflammatory activity within the atrial myocardium, may also face an increased risk of atrial fibrillation [29,30]. Some patients were observed to have extraordinarily enlarged left atrium (LA) [31]. Apart from a greater haemodynamic burden on the LA, prolonged autoimmune-related inflammation could also favor the LA remodelling in RHD patients.…”

Section: Rheumatic Heart Disease (Rhd)mentioning

confidence: 99%

The Role of Inflammation and Oxidative Stress in Rheumatic Heart Disease

Franczyk

Gluba-Brzózka

Rysz-Górzyńska

et al. 2022

IJMS

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Rheumatic heart disease (RHD), an acquired valvular disease, remains an important cause of morbidity and mortality in developing countries. This chronic illness starts from untreated streptococcal throat infection, resulting in acute rheumatic fever (ARF) in susceptible individuals. Repeated infections lead to a chronic phase characterized by the damage of heart valves. Inflammation has been found to play important role in the development of this disease. All the studies presented in this review clearly show the involvement of the inflammatory state in the progression of this disease. However, the exact role of cytokines in inflammation sites remains to be examined, since most studies have so far focused on peripheral blood. Such analysis would provide information on inflammatory mechanisms in situ.

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“…The GLA is a severe dilatation of the LA that produces various complications compromising hemodynamic stability. 9 , 10 There is no standardized definition of GLA throughout the literature, and it tends to differ across the published series. 2 , 9 , 11 The pathophysiology is still under debate, although GLA occurs mainly in patients with MV insufficiency and stenosis 11 and is more frequent in patients with rheumatic MV disease regurgitation than in nonrheumatic patients.…”

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confidence: 99%