Large congenital epulis of newborn

Chami, Rabih G.; Wang, Hansen S.

doi:10.1016/s0022-3468(86)80091-4

Cited by 23 publications

(22 citation statements)

References 7 publications

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“…Although its indolent nature CGCT can be sufficiently large or multiple [8]. In the case of feeding problems with a risk of aspiration pneumonia, respiratory obstruction, bleeding problems due to external trauma requires early surgical removal [2,9,17]. Neither recurrence nor malignancy has been reported, even after incomplete excision [10].…”

Section: Discussionmentioning

confidence: 99%

“…CGCT is unusual benign oral cavity tumour that is present in the alveolar mucosa at birth [1,2]. These lesions show a benign behaviour and no recurrent or metastatic lesion has been reported [3].…”

Section: Introductionmentioning

confidence: 99%

“…These lesions show a benign behaviour and no recurrent or metastatic lesion has been reported [3]. It's seen three times more frequently in the maxillary alveolus than in the mandibular alveolus and the female to male ratio is 10:1 [1,2,4]. Its diagnosis is not usually difficult because its typical morphological occurrence on alveolar ridge in newborn, and never shows further growth after birth [5].…”

Section: Introductionmentioning

confidence: 99%

“…The etiology of the condition is unknown. Several theories have been suggested, namely, myoblastic, odontogenic, neurogenic, fibroblastic, histiocytic and endocrinologic [1,2].…”

Section: Introductionmentioning

confidence: 99%

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Obstructive congenital gingival granular cell tumour

Bilen

Alaybeyoğlu

Arslan

et al. 2004

International Journal of Pediatric Otorhinolaryngology

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The etiology of the condition is unknown. Several theories have been suggested, namely, myoblastic, odontogenic, neurogenic, fibroblastic, histiocytic and endocrinologic [1,2].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Obstructive congenital gingival granular cell tumour

Bilen

Alaybeyoğlu

Arslan

et al. 2004

International Journal of Pediatric Otorhinolaryngology

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“…CGCE is predominantly a lesion of females, with a male-to-female ratio of 1:10 [2]. Clinically, it usually presents as a pedunculated nodule of less than 2 cm in size [3,4], although larger lesions have been reported, some even large enough to protrude from the mouth [5][6][7]. Most lesions are single, but multiple lesions may also occur on the same or different alveolar ridges [2,4].…”

Section: Introductionmentioning

confidence: 99%

Congenital granular cell epulis presents an immunohistochemical profile that distinguishes it from the granular cell tumor of the adult

2009

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Congenital granular cell epulis (CGCE), a rare benign lesion arising from the mucosa of the alveolar ridges of the jaws in newborns, has a clinical course characterized by lack of further growth after birth. Histomorphologically, it resembles a granular cell tumor (GCT) of the adult. The histogenesis of this lesion is unclear. We submitted a series of five CGCEs to a large panel of antibodies in order to trace the origin of the constituent granular cells. The resultant immunohistochemical profile showed positivity of these cells to vimentin, NKI/C3, and PGP9.5. This does not confirm any particular cell type for the histogenetic origin of CGCE but may rather reflect a local metabolic or reactive change, providing supporting evidence that the lesion is of a non-neoplastic nature. In addition, the granular cells were non-reactive for S-100, NGFR/p75, and inhibin-alpha, which further contributes to the distinction between a CGCE and the adult GCT.

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A patient with large congenital epulis in the maxillary and mandibular anterior areas accompanied by impaired suckling

Adachi

Yamamoto

Kishimoto

et al. 2022

Oral Science International

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Background Congenital epulis is a rare tumor of the newborns. Case Presentation We found a case of soft elastic pedunculated masses in the left maxillary anterior (26 × 14 × 11 mm) and left mandibular anterior (55 × 44 × 11 mm) areas, protruding out of the oral cavity. The large multiple masses interfered with suckling. These masses were excised using a carbon dioxide laser under general anesthesia. They were diagnosed histopathologically and immunocamically as congenital granular cell epulis. These were no complication after surgery. Conclusion We report a 1‐day old female infant with large congenital epulis in the left anterior deciduous tooth regions of the upper and lower jaws, accompanying impaired suckling. The histopathological finding of masses was congenital granular cell epulis.

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Large congenital epulis of newborn

Cited by 23 publications

References 7 publications

Obstructive congenital gingival granular cell tumour

Obstructive congenital gingival granular cell tumour

Congenital granular cell epulis presents an immunohistochemical profile that distinguishes it from the granular cell tumor of the adult

A patient with large congenital epulis in the maxillary and mandibular anterior areas accompanied by impaired suckling

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