Laparoscopic radiofrequency thermal ablation: A new approach to symptomatic uterine myomas

Bergamini, Valentino; Ghezzi, Fabio; Cromi, Antonella; Bellini, Gaia; Zanconato, Giovanni; Scarperi, S.; Franchi, Massimo Piergiuseppe

doi:10.1016/j.ajog.2004.10.591

Cited by 77 publications

(56 citation statements)

References 21 publications

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“…The preliminary results of the first 18 women have been reported elsewhere [2]. Only patients who have now completed at least the one-year follow-up assessment were included in the present study.…”

Section: Methodsmentioning

confidence: 98%

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Midterm outcome of radiofrequency thermal ablation for symptomatic uterine myomas

et al. 2007

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Section: Methodsmentioning

confidence: 98%

“…We previously reported our preliminary observations in a series of women with symptomatic uterine myomas who underwent radiofrequency ablation (RFA) under laparoscopic guidance [2]. In that initial report the follow-up interval ranged from 3 to 12 months.…”

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confidence: 99%

Midterm outcome of radiofrequency thermal ablation for symptomatic uterine myomas

et al. 2007

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“…Recent trend has been toward nonsurgical approaches such as GnRH hormone analogs/agonists, RU 486 [4] or selective uterine artery embolization [5], laparoscopic cryoablation [6,7], radiofrequency thermal ablation [8], and MRGUs [9,10]. Cervical fibroids are a separate class by themselves and account for 2-8 % of cases usually single.…”

Section: Risk Factorsmentioning

confidence: 99%

Clinicopathological Study of Uterine Leiomyomas: A Multicentric Study in Rural Population

Dutta²,

Dutta³

2015

J Obstet Gynecol India

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Background and Objectives Leiomyoma of uterus forms the most common type of benign tumor of uterus and also the most common pelvic tumor in women. The symptomatology continues to be variable. Surgery has for long been the main mode of therapy for the myomas. For women who wish to retain the uterus for future pregnancies or other reasons, myomectomy is preferred. Recent trend has been toward nonsurgical approaches like GnRH hormone analogs/agonists, RU 486, or selective uterine artery embolization, laparoscopic cryoablation, radiofrequency thermal ablation, and MRGUs. This multicentric study was an attempt to analyze the clinicopathological spectrum in cases of leiomyoma of the uterus at Cheluvamba Hospital, Adichunchanagiri Institute of Medical Sciences, and to know regarding the pattern of presentation, pathological correlation, with type of fibroid, and endometrial and ovarian changes. Results Leiomyoma is the most common benign tumor of the uterus and commonly affects the women of childbearing age, most commonly in the third decade, 55 %. The most common mode of presentation was menstrual disturbances (76 %), among which menorrhagia was seen in 54 % of the cases. Primary infertility was seen in 15 % of the patients. Intramural fibroids were the most common variety occurring in 60 % of the cases. Endometrial pattern was proliferative in 66.3 %. Cystic ovaries were seen in 8 % of the patients, adenomyosis in 16 % indicating hyperestrogenism. Conclusion Fibromyoma (leiomyoma) is the most common benign tumor of the pelvis. It commonly affects the women of child-bearing age, mostly in the third decade and is most commonly seen in multipara. The most common mode of presentation is menstrual disturbances. Intramural fibroid is the most common variety. The proliferative and hyperplastic endometrium was commonly reported. The presence of proliferative endometrium, adenomyosis, and cystic ovaries all are indicative of hyperestrogenic state associated with development of fibroids.

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“…3 Hysterectomy has been the main mode of therapy for leiomyomas and adenomyosis. However, medical technology advancements have made less invasive treatment options available, such as uterine artery embolization (UAE), [4][5][6] high-intensity focused ultrasound (HIFU), [7][8][9] radiofrequency (RF) 10 and percutaneous microwave ablation (PMWA). 11,12 PMWA is a minimally invasive technique for the treatment of uterine leiomyomas and adenomyosis by inducing tissue necrosis through heat.…”

Section: Advances In Knowledgementioning

confidence: 99%

Feasibility study on energy prediction of microwave ablation upon uterine adenomyosis and leiomyomas by MRI

Xia

Zhu²,

Han³

et al. 2014

BJR

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Objective: To evaluate the feasibility of energy prediction of percutaneous microwave ablation (PMWA) upon uterine leiomyomas and adenomyosis by MRI. Methods: 63 patients (49 patients with 49 uterine leiomyomas and 14 patients with adenomyosis) who underwent ultrasound-guided PMWA treatment were studied during the period from June 2011 to December 2012. Before PMWA, contrast-enhanced MRI (ceMRI) was performed for all of the patients. Based on the signal intensity (SI) of T 2 weighted MRI, uterine leiomyomas were classified as hypointense, isointense and hyperintense. During ablation, the output energy of the microwave was set at 50 W, and T11a microwave antennas were used. ceMRI was performed within 7 days after PMWA treatment. Non-perfused volume and energy required per unit volume were analysed statistically.Results: When unit volume of lesions was ablated, uterine adenomyosis needed more energy than did uterine leiomyomas, and hyperintense uterine leiomyomas needed more energy than did hypointense pattern.Conclusions: MRI SI of uterine leiomyomas and uterine adenomyosis can be used to predict PMWA energy. Advances in knowledge:The conclusions indicate that MRI SI can be used to perform pre-treatment planning, which will make the treatment more precise.

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Laparoscopic radiofrequency thermal ablation: A new approach to symptomatic uterine myomas

Cited by 77 publications

References 21 publications

Midterm outcome of radiofrequency thermal ablation for symptomatic uterine myomas

Midterm outcome of radiofrequency thermal ablation for symptomatic uterine myomas

Clinicopathological Study of Uterine Leiomyomas: A Multicentric Study in Rural Population

Feasibility study on energy prediction of microwave ablation upon uterine adenomyosis and leiomyomas by MRI

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