Lanthanide Nanoparticles: From Design toward Bioimaging and Therapy

Polyaniline-coated upconversion nanoparticles with upconverting luminescent and photothermal conversion properties for photothermal cancer therapy

“…31 Thus, lanthanidebased upconversion nanoparticles (UCNPs) have special optical characteristics, such as sharp emission lines, large anti-Stokes shifts of several hundred nanometers, and the absence of autofluorescence in biosamples. [32][33][34][35][36][37][38] Therefore, UCNPs have been recently used as building blocks in the construction of multimodal contrast agents for imagingguided therapy. [39][40][41][42][43][44][45] In the current study, upconversion nanoparticles (UCNPs) were first prepared by a typical solvothermal method.…”

Physical Background for Luminescence Thermometry Sensors Based on Pr3+:LaF3 Crystalline Particles

“…The most widespread is the subclass of luminescent nanothermometers based on the analysis of relative fluorescence intensity between the different emission bands corresponding to the suitable transitions [1,9,13]. Among the most usable materials for luminescent nanothermometers such as quantum dots (QD) and dye-based luminescent nanothermometers, the rare-earth based materials have a special place mainly because of their excellent photostability, long luminescent lifetimes, sharp emission bands, and low toxicity which is highly important for biomedical application, for example, in photothermal and photodynamic therapies [14]. Indeed, in biomedicine, the luminescent nanothermometers should be nontoxic and stay chemically stable under light irradiation so that toxic components of reaction product are not delivered to the cells [1].…”

Europium-doped NaGd(WO4)2 nanophosphors: synthesis, luminescence and their coating with fluorescein for pH sensing

“…[1][2][3] and more recently, the biotechnological fields (sensors, imaging, therapy, etc.). 4 These research activities have been mainly justified on the basis of the advantageous characteristics of such materials when compared with other luminescent compounds such as quantum dots, which include high chemical and thermal stability, high luminescence efficiency and low toxicity. They suffer however from a main drawback related to the low intensity of their emissions, which is due to the low absorption coefficient associated to the electronic transitions involved in the luminescence process of the Ln cations.…”

“…The Eu concentration has been optimized through the analysis of the luminescence dynamics (lifetime measurements). With these nanophosphors we have also developed a wide range (4)(5)(6)(7)(8)(9)(10) pH-sensitive nanosensor by coating the Eu 3+ -doped wolframate based NPs with fluorescein, a fluorescent dye with a pH-dependent emission. [24][25] In this case, the pH Thermogravimetric analysis (TGA) was performed in air at a heating rate of 10°C min -1 , using a Q600 TA Instrument.…”