Lanthanide-functionalized silver nanoparticles for detection of an anthrax biomarker and test paper fabrication

Ratiometric fluorescent detection of biomakers for biological warfare agents with carbon dots chelated europium-based nanoscale coordination polymers

“…The result was comparable to that of the previously reported lanthanide-based fluorescent sensors or ratiometric fluorescent sensors (Table 1) [26,[32][33][34][35][36][37]61]. Taking automated anthrax smoke detector as an example, the detection limit was lower (0.2 nM) than that of the CDs@Eu/GMP, but the linear range was narrower (10-100 nM) [26].…”

“…Methods such as high-pressure liquid chromatography, electrochemical detection, surface enhanced Raman spectroscopy (SERS), polymerase chain reactions (PCR), immunoassays and fluorescence have been used to detect DPA [29][30][31][32][33][34][35][36][37][38]. For example, Li and Wang have designed a ratiometric fluorescent nanosensor constructed by fluorescence dyes chelating with lanthanide ion (Ln 3+ ) for DPA detection [32,33,37].…”

BSA–AuNPs@Tb–AMP metal–organic frameworks for ratiometric fluorescence detection of DPA and Hg2+

“…As shown in Tables S1 and S2, the designed probe displayed excellent properties as compared with other DPA and Hg 2+ sensors . Such good performances might be ascribed to the more efficient use of the surface area of the core‐shell structure of BSA–AuNPs@Tb–AMP MOFs and the self‐calibration of the concentration from ratiometric fluorescence measurement …”

“…It is really worth pursuing high sensitivity methods for Hg 2+ detection because Hg 2+ is non‐biodegradable and bioaccumulables through the food chain and therefore could damage the brain, kidneys, and the nervous system . Conversely, DPA detection is also of great importance because it is the major components in protective layers of Bacillus anthracis spores . Bacillus anthracis spores, which have resulted in large numbers of population deaths throughout history, can be released into bulk solution by physical hydrolysis, chemical hydrolysis or germination and their mass can be calculated using their DPA concentration .…”

Nanomaterial-functionalized Cellulose: Design, Characterization and Analytical Applications

“…Another commonly used fluorescent agent is 2,3-diaminophenazine which can be oxidized from o-phenylenediamine in the presence of Ag(I) or Au(II) ions 86 to create fluorescent light. Lanthanide series ions such as Tb 3+ has been utilized to generate a fluorescent response for detection of soluble uPAR (an important tumor marker) 87 or dipicolinic acid (DPA), 88 an anthrax biomarker. Fluorescent nanospheres of tris 8-hydroxyquinoline aluminum (Alq3), a complex between aluminum and three 8-hydroxyquinoline molecules have been used as fluorescent probes to detect 2,4,6-trinitrotoluene (TNT) and 2,4,6-trinitrophenol (TNP) explosives through fluorescence quenching.…”