Langerhans' cell histiocytosis of the temporal bone in an adult with central diabetes insipidus

Allen, Amanda; Matrova, Elza; Özgen, Burçe; Redleaf, Miriam; Emmadi, Rajyasree; Saran, Nitu

doi:10.1016/j.radcr.2019.03.040

Cited by 7 publications

(8 citation statements)

References 11 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We report the case of a 2-year-old child with HCL with bilateral temporal bone involvement associated with central pituitary involvement responsible for diabetes insipidus. Rare similar cases have been reported [7]- [9].…”

Section: Discussionmentioning

confidence: 59%

Langerhans Cell Histiocytosis of the Temporal Bone in Children: Two Cases Report

Labani¹,

Oulghoul²,

Benhoummad³

et al. 2021

EJMED

View full text Add to dashboard Cite

Langerhans cell histiocytosis is a rare hematologic disease due to multiplication and accumulation of Langerhans cells, which are immature dendritic cells. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisystem disease. We report 2 cases confirmed by Histological and immunohistochemical evaluation of temporal bone biopsies. The first case is a 2-year-old child with chronic bilateral otorrhea and polyuria-polydipsia syndrome. Physical examination showed bilateral retroauricular redness and induration with filling all of the right and left external ear canal. Computed tomography showed osseous lysis of the temporal bone bilaterally. Magnetic resonance imaging of the brain showed the presence of pituitary infiltration. The second case is 2-year-old girl with chronic left otorrhea. Clinical examination objectified the presence of redness and induration in the left mastoid with the presence of an inflammatory polyp filling the entire left external auditory canal. Computed tomography revealed a left temporal bone lysis. Both patients were treated with chemotherapy.

show abstract

Section: Discussionmentioning

confidence: 59%

Langerhans Cell Histiocytosis of the Temporal Bone in Children: Two Cases Report

Labani¹,

Oulghoul²,

Benhoummad³

et al. 2021

EJMED

View full text Add to dashboard Cite

show abstract

“…We report the case of a 2-year-old child with LH with bilateral temporal bone involvement associated with central pituitary involvement responsible for diabetes insipidus. Rare cases with similar presentation have been reported [8][9][10].…”

Section: Discussionmentioning

confidence: 94%

Langerhans Cell Histiocytosis of the Temporal Bone in a Child with Central Diabetes Insipidus

LAGRINE¹,

Labani²,

Fakiri³

et al. 2020

J Pediatr Res Rev Rep

View full text Add to dashboard Cite

Langerhans cell histiocytosis is a rare clonal disease defined by an accumulation of dendritic cells with Langerhans cell immunological properties within different organs of the body. We intend to describe a new case of Langerhans cell histiocytosis of the temporal bone in a child with central diabetes insipidus. The child presented the polyuria-polydipsia syndrome for 6 months with Chronic bilateral otorrhea. On physical examination,there were bilateral retroauricular redness and induration. The otoscopy visualized inflammatory polyps filling all of the right and left external ear canal. Biological exploration confirmed the central diabetes insipidus. Magnetic resonance imaging of the brain showed the presence of pituitary infiltration. Computed tomography showed osseous lysis of the temporal bone bilaterally. A retroauricular biopsy was performed under general anesthesia. Histological and immunohistochemical evaluation confirmed the diagnosis of Langerhans cell histiocytosis

show abstract

“…The disease process is, therefore, usually classified as three clinical variations based on organ involvement. These categories are named as eosinophilic granuloma, usually a solitary osseous lesion; Hand Schuller-Christian disease, the chronic recurrent form, which classically shows a triad of a skull lesion, exophthalmos, and diabetes insipidus; and the fulminant formation named as Letterer Siwe disease-multiple organ involvement [8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Intradural Langerhans' Cell Histiocytosis Invading Frontal Bone of Skull: A Case Report with A Brief Review

Sunder¹,

Mukesh²,

Deepika³

2020

ACMCR

View full text Add to dashboard Cite

Langerhans' cell histiocytosis of the temporal bone in an adult with central diabetes insipidus

Cited by 7 publications

References 11 publications

Langerhans Cell Histiocytosis of the Temporal Bone in Children: Two Cases Report

Langerhans Cell Histiocytosis of the Temporal Bone in Children: Two Cases Report

Langerhans Cell Histiocytosis of the Temporal Bone in a Child with Central Diabetes Insipidus

Intradural Langerhans' Cell Histiocytosis Invading Frontal Bone of Skull: A Case Report with A Brief Review

Contact Info

Product

Resources

About