Landmark article May 19, 1945: The surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia. By Alfred Blalock and Helen B. Taussig

Blalock, Alfred

doi:10.1001/jama.251.16.2123

Cited by 224 publications

(237 citation statements)

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“…Since 1977, modified Waterston's shunt operation using ETFE graft has been performed in our institute and its results have improved (Gazzangia et al 1976). In selected patients, Blalock-Taussig's shunt procedure has also proved successful (Blalock and Taussig 1945). We reviewed medical treatment during the pre-operative period and surgical treatment during the last ten years.…”

Section: Discussionmentioning

confidence: 99%

Effects of prostaglandin E1 infusion in the pre-operative management of critical congenital heart disease.

Ohara

Ogata

Fujiyama

et al. 1985

Tohoku J. Exp. Med.

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Prostaglandin E1(PGE1) was administered to 27 infants in whom pulmonary or systemic blood flow was entirely or significantly dependent upon the patency of the ductus arteriosus. In 12 patients with pulmonary atresia or severe pulmonary stenosis, PGE1 infusion was followed by an improvement in hypoxemia and acidemia (group I). In 2 patients with left ventricular outflow-tract obstruction, PGE1 infusion was followed by an improvement in arterial blood pressure, peripheral perfusion and urine output (group II). In 5 patients with d-transposition of the great arteries and intact ventricular septum who had persistent severe hypoxemia after creation of an interatrial communication, PGE1 infusion improved the arterial oxygenation with dilatation of the ductus arteriosus (group III). Seven patients (3 of group I, 2 of group II and 2 of group III) failed to respond to PGE1. There were no fatal side effects. It is concluded that PGE1 therapy is highly effective in stabilizing pre-operative conditions of infants with ductus-dependent congenital heaat disease. prostaglandin E1 i ductus-dependent congenital heart disease ; pre-operative management Adequate pulmonary or systemic blood flow is dependent upon the patency of the ductus arteriosus in some of the critically ill infants with congenital heart disease. Partial or complete closure of the ductus after birth results in hypoxemia or severe heart failure with the progressive development of acidemia. Although palliative or corrective surgical procedures were available, mortality in these infants was high, because of their deteriorated pre-operative conditions and of the difficulties of the surgical techniques. Elliott et al. (1975) and Olley et al. (19Th, 1976) reported that administration of prostaglandins E1 (POE1) and E2 (PGE2) to such infants improved the deteriorated conditions. Following their reports, several authors have recongn-

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Section: Discussionmentioning

confidence: 99%

Effects of prostaglandin E1 infusion in the pre-operative management of critical congenital heart disease.

Ohara

Ogata

Fujiyama

et al. 1985

Tohoku J. Exp. Med.

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show abstract

“…With Dr Alfred Blalock as the surgeon and the wisdom of his assistant Vivien Thomas, Taussig and Blalock revolutionized the care of the cyanotic child with the construction of the subclavian arteryto-pulmonary artery end-to-side anastomosis, thus augmenting pulmonary blood flow, and published their early experience in 1945. 4 Coarctation of the aorta was successfully repaired in 1945 by Crafoord and Nylin of Stockholm 5 ; Brock, using a "closed" technique, performed a pulmonary valvotomy 6 ; and in 1950, Blalock and Hanlon performed an atrial septectomy using the surgical clamp designed by Vivien Thomas. 7 And then came the last half of the 20th century.…”

mentioning

confidence: 99%

Pediatric Cardiology and Cardiovascular Surgery: 1950-2000

Freedom

Lock²,

Bricker³

2000

Circulation

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“…Entwicklung nach Herlong [14] I. Atresie der gemeinsamen Vorhofes, kommt es zu einer Shuntumkehr in einen Rechts-Links-Shunt, der dann zum klinischen Bild der sogenannten "late cyanosis" (H. Taussig) führen kann [15]. Der linke Vorhof und Ventrikel erscheinen bei großen Defekten eher zierlich [16].…”

Section: Tabelle 1: Einteilung Der Lungenvenenfehlmündungen Nach Der unclassified

15.6 Partielle Lungenvenenfehlmündung

Haas¹,

Kleideiter²

2011

Kinderkardiologie

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Landmark article May 19, 1945: The surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia. By Alfred Blalock and Helen B. Taussig

Cited by 224 publications

References 0 publications

Effects of prostaglandin E1 infusion in the pre-operative management of critical congenital heart disease.

Effects of prostaglandin E1 infusion in the pre-operative management of critical congenital heart disease.

Pediatric Cardiology and Cardiovascular Surgery: 1950-2000

15.6 Partielle Lungenvenenfehlmündung

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