In this research, the connection between land use and energy has been discussed from two points of view, i.e., the impacts of energy on land use and the impacts of land use on energy. This research identified several direct and indirect land use changes that occur by clearing vegetation, destroying top soils, and relocating human populations during the different stages of extraction, deposition, and transportation of fossil fuels and uranium ore; and during the establishment of renewable energy sources including wind turbines, hydro-power plants, and associated structures (highways, dams, culverts, tunnels, power station infrastructure, and energy transmission networks). Likewise, feedstock cultivation, processing, and transportation to biomass plants, as well as the production of biodiesel from municipal solid waste, require accessible land resources that further contribute to global land-use change. In the case of the impacts of land use on energy, mixed use development was found to be one of the most efficient approaches to achieve energy efficiency. Similarly, energy demand for motorized travel can also be reduced with the development of urban blocks and transit-oriented development. Furthermore, integrated combined heat and power systems, green space, and energy-supporting land use regulations were identified as energy savings strategies that may aid in achieving energy efficiency and ensuring sustainable development.