Lactulose-Any Clinical Benefits beyond Constipation Relief? A Pilot Study in Infants with Allergic Symptoms

Rinne, Minna; Kirjavainen, Pirkka V.; Salminen, Seppo; Isolauri, Erika

doi:10.12938/bifidus1996.22.155

Cited by 6 publications

(1 citation statement)

References 12 publications

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“…The most commonly used nonmilk NDOs in pediatric trials are: (Alliet et al, 2007;Arslanoglu et al, 2007a,b;Bongers et al, 2007;Brunser et al, 2006;Bruzzese et al, 2006;Costalos et al, 2008;Euler et al, 2005;Indrio et al, 2007;Kapiki et al, 2007;Moore et al, 2003;Rinne et al, 2003Rinne et al, , 2005aSavino et al, 2003Savino et al, , 2005van Hoffen et al, 2009;Waligora-Dupriet et al, 2007;Ziegler et al, 2007) The amount of fecal bifidobacteria, their percentage compared to the total number of bacteria, and the production of SCFA are generally used in evaluating their prebiotic effect. They can be extracted from natural sources, synthesized from monomers and/or small oligosaccharides, or produced by natural polymer hydrolysis.…”

Section: Nonmilk Oligosaccharidesmentioning

confidence: 99%

Prebiotics and Probiotics in Infant Nutrition

Zuppa

Alighieri

Scorrano³

et al. 2016

Probiotics, Prebiotics, and Synbiotics

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Section: Nonmilk Oligosaccharidesmentioning

confidence: 99%

Prebiotics and Probiotics in Infant Nutrition

Zuppa

Alighieri

Scorrano³

et al. 2016

Probiotics, Prebiotics, and Synbiotics

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Medical, nutritional and technological properties of lactulose. An update

Schümann

2002

European Journal of Nutrition

132

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The undigestable disaccharide lactulose has been in medical use for over 40 years, mainly in the treatment of portosystemic encephalopathy and of constipation. Pharmacodynamics of lactulose make it an efficacious and safe drug in these indications. But the reason for its numerous potential benefits are under research now. The major principle of action is the promotion of growth and activity of lactic acid bacteria in the gut which counteract detrimental species such as clostridia or salmonellae. This shows that prebiotic action, if used accordingly, can have medically significant effects. The mechanism of action, medical and prebiotic effects, veterinary uses, and technological properties of lactulose, e. g. in yoghurt production are reviewed.

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