Abstract:Lactotransferrin, also known as lactoferrin, is an iron binding glycoprotein that
displays antiviral activity against many different infectious agents, including human
immunodeficiency virus (HIV)-1. Lactotransferrin is present in the breast milk and in
the female genitourinary mucosa and it has been hypothesised as a possible candidate
to prevent mother-to-child HIV-1 transmission. To verify if two functional
polymorphisms, Thr29Ala and Arg47Lys, in the lactotransferrin encoding gene (LTF)
could affect HIV-1 … Show more
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