Lactic acid bacteria as probiotic candidate and their application

riaz, Muhammad shahid; Shaheen, Tayyaba; Batool, Nagina; Saleem, Semhab; Hayat, Fakhar

doi:10.15412/j.jbtw.01041202

Cited by 2 publications

(1 citation statement)

References 47 publications

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“…LAB including species of Enterococcus, Lactobacillus, Pediococcus, Streptococcus, Lactococcus, Vagococcus, Leuconostoc, Oenococcus, Weissella, Carnobacterium and Tetragenococcus are natural microflora of both humans and animals GIT [4, 5]. They have been reported to possess a broad spectrum of beneficial and health promoting properties which dramatically influences the host microbial intestinal balance and general performance [6, 7]. Although the effectiveness of LAB strains used as probiotics are species and/or strains dependent, they must nevertheless meet all the necessary criteria needed for acceptability as probiotics as earlier described [8].…”

Section: Introductionmentioning

confidence: 99%

Isolation, characterization, and assessment of lactic acid bacteria toward their selection as poultry probiotics

Reuben¹,

Roy²,

Sarkar³

et al. 2019

BMC Microbiol

186

133

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BackgroundProbiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host, are now accepted as suitable alternatives to antibiotics in the control of animal infections and improving animal production. Lactic acid bacteria (LAB) with remarkable functional properties have been evaluated in different studies as possible probiotic candidates. The purpose of this study was to isolate, characterize and assess the potentials of LAB from poultry gastrointestinal tract as potential poultry probiotics.ResultsPotential LAB probiotics were isolated from broilers, characterized and evaluated for probiotic properties including antagonistic activity (against Escherichia coli, E. coli O157: H7, Enterococcus faecalis, Salmonella Typhimurium, S. Enteritidis and Listeria monocytogenes), survivability in simulated gastric juice, tolerance to phenol and bile salts, adhesion to ileum epithelial cells, auto and co-aggregation, hydrophobicity, α–glucosidase inhibitory activity, and antibiotic susceptibility tests. Most promising LAB strains with excellent probiotic potentials were identified by API 50 CHL and 16S rRNA sequencing as Lactobacillus reuteri I2, Pediococcus acidilactici I5, P. acidilactici I8, P. acidilactici c3, P. pentosaceus I13, and Enterococcus faecium c14. They inhibited all the pathogens tested with zones of inhibition ranging from 12.5 ± 0.71 to 20 ± 0 mm, and competitively excluded (P < 0.05) the pathogens examined while adhering to ileum epithelial cells with viable counts of 3.0 to 6.0 Log CFU/ml. The selected LAB strains also showed significant (P < 0.005) auto and co-aggregation abilities with α-glucosidase inhibitory activity ranging from 12.5 to 92.0%. The antibiotic susceptibility test showed 100.00% resistance of the LAB strains to oxacillin, with multiple antibiotic resistance indices above 0.5.ConclusionThe selected LAB strains are ideal probiotic candidates which can be applied in the field for the improvement of poultry performance and control of pathogens in poultry, hence curtailing further transmission to humans.

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Section: Introductionmentioning

confidence: 99%

Isolation, characterization, and assessment of lactic acid bacteria toward their selection as poultry probiotics

Reuben¹,

Roy²,

Sarkar³

et al. 2019

BMC Microbiol

186

133

View full text Add to dashboard Cite

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Impact of dietary compounds on cancer-related gut microbiota and microRNA

Rajoka

Jin

Zhao

et al. 2018

Appl Microbiol Biotechnol

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Cancer is one of the most common causes of death worldwide. Extensive research has been conducted on cancer; regardless, the link between cancer and diet remains undetermined. Recent studies have emphasized the importance of miRNAs in cancer-associated pathways from the perspective of dietary modulation. We highlighted the recent data on dietary modulation of gut microbiota and miRNAs related to cancer on the basis of recently published results. The targets of miRNAs are oncogenes or tumor suppressors that mediate the progression and initiation of carcinogenesis. Different miRNAs display complex expression profiles in response to dietary manipulation. Various dietary components, such as fatty acids, resveratrol, isothiocyanate, and curcumin, have been effectively used in cancer prevention and treatment. This potency is attributed to the capability of these components to alter miRNA expression, thereby modulating the vital pathways involved in metastasis, invasion, apoptosis, tumor growth, and cell proliferation.

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Lactic acid bacteria as probiotic candidate and their application

Cited by 2 publications

References 47 publications

Isolation, characterization, and assessment of lactic acid bacteria toward their selection as poultry probiotics

Isolation, characterization, and assessment of lactic acid bacteria toward their selection as poultry probiotics

Impact of dietary compounds on cancer-related gut microbiota and microRNA

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