Lack of detectable allergenicity of transgenic maize and soya samples

Batista, Rita; Nunes, Baltazar; Carmo, Manuela; Cardoso, Carlos; José, Helena São; Almeida, Álvaro; Manique, Alda; Bento, L.; Ricardo, Cândido Pinto; Oliveira, M. Margarida

doi:10.1016/j.jaci.2005.04.014

Cited by 60 publications

(39 citation statements)

References 35 publications

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“…One of the significiant examples of this is "StarLink" incident in USA.StarLink is the trading name of a genetically modified corn developed by Aventis Crop Science Company. This corn includes Cry9C protein and it is defined as "a potential alergenic" by US Environmental Protection Agency (EPA) so in 1998 EPA stated that StarLink can only be used as animal feed or in industry but it cannot be used as human food [34,35]. According to Ozdogan and Ekmen (2002) soyabean given Brazi-nut gene to enhance nutritional value caused severe allergic reaction and was prohibited in 1994 [36].…”

Section: Allergymentioning

confidence: 99%

Genetically Modified Foods and the Probable Risks on Human Health

Ozkok¹

2015

IJNFS

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Abstract:Changing existing features of living beings or giving new features to them by changing the natural gene sequence through biotechnological methods is called "genetically modified organisms", in short "GMO". Nowadays, lots of food consumed is either totally genetically modified food or a type of food including food components produced by gene modification technology. Improving nutritive quality, extracting aminoacids as food additives and enzymes in microorganisms, increasing retention period and organeolepticquality, new planting methods, precocity, resistance against disease, stres, herbicide and viruses, better waste utilization, saving of soil, water and energy, creating new bioprocesses are the probable advantages of genetically modified organisms, whereas changes in food quality, genetic diversity threats, unfair competition between organic suppliers and traditional suppliers, noncompulsory awarness raising in some countries, food industry dominated only by a few big companies, biopiracy and consuming of natural resources by foreigners are among the probable disadvantages of genetically modified foods. Among the hesitations about GMO widely used and consumed all over the world, the most topical issue is the probable health risks caused by GMOs which are consumed as food. Through gene transfer, some features causing allergy and disease can be carried from other organism and as a consequence of this, there may be the risk of finding unexpected biochemical products in transgenic products. As uncertainities about GM foods continue, studies conducted in many countries have revealed that there are many differences among people's information, attitude and behaviour toward this issue in various countries. Modified food is affected by factors such as education and knowledge level, risk perception, socioeconomic status, media, etc. Besides, level of income and occupation follow them. In the present compilation based on literature, it is aimed to summarize the facts related to GMO. For this reason, the probable risk factors for human health, consumer reaction, the pros and cons of GMOs stated by defining GM generally are explained in the study. With the present study aiming to reveal GM foods and their probable health risks for human, it is concluded that consumers accept the existence of biotechnologic applications but they are not familiar with these products and also consumers have great considerations about GMO produced by genetic modification and they display a negative attitude toward GM products.Consumer should be informed due to all these reasons. Media organs, therefore, have a significant role as the source of information and they will also contribute to raise awareness in society.

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Section: Allergymentioning

confidence: 99%

Genetically Modified Foods and the Probable Risks on Human Health

Ozkok¹

2015

IJNFS

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“…Also, there have been associated allergic reactions to the consumption of modified soybean (Burks et al, 1988;Ogawa et al, 1993;Burks & Fuchs, 1995). Nevertheless Batiste et al in 2005, reported a study where volunteers did not showed allergic reaction after consumption of modified soybean and modified maize. Nevertheless, the benefits of the modified soybean exceed in much to the adverse effects.…”

Section: Risks Associated With the Transgenic Seedsmentioning

confidence: 99%

Transgenic Residues in Soybean-based Foods

Chávez‐González¹,

Flores-Gallegos²,

García-Lazalde³

et al. 2011

Soybean - Molecular Aspects of Breeding

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“…Thus, no significant level of IgE antibodies specific to the Cry1Ab protein could be found in the studied food-allergic patients. Batista et al (2005) performed skin prick tests with extracts of maize MON810 on children with food and inhalant allergy and individuals with asthma-rhinitis. None of the individuals undergoing tests reacted differently to the MON810 and the non-transgenic maize samples studied.…”

Section: Assessment Of Allergenicity Of the Whole Gm Plantmentioning

confidence: 99%

Applications (EFSA‐GMO‐RX‐MON810) for renewal of authorisation for the continued marketing of (1) existing food and food ingredients produced from genetically modified insect resistant maize MON810; (2) feed consisting of and/or containing maize MON810, including the use of seed for cultivation; and of (3) food and feed additives, and feed materials produced from maize MON810, all under Regulation (EC) No 1829/2003 from Monsanto

2009

EFS2

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SUMMARYThis document provides a scientific opinion of the Scientific Panel on Genetically Modified Organisms (GMO Panel) of the European Food Safety Authority (EFSA) on 3 applications 1 For citation purposes: Scientific Opinion of the Panel on Genetically Modified Organisms on applications (EFSA-GMO-RX-MON810) for the renewal of authorisation for the continued marketing of (1) existing food and food ingredients produced from genetically modified insect resistant maize MON810; (2) feed consisting of and/or containing maize MON810, including the use of seed for cultivation; and of (3) (1) existing food and food ingredients produced from genetically modified (GM) maize MON810 (Unique Identifier MON-ØØ81Ø-6); (2) feed consisting of and/or containing maize MON810, including the use of seed for cultivation; and of (3) food and feed additives, and feed materials produced from maize MON810, developed by Monsanto to provide resistance to lepidopteran target pests.The scopes of the 3 renewal applications cover the continued marketing of:-existing food and food ingredients produced from maize MON810 (Reference EFSA-GMO-RX-MON810 [8-1a] ) that have been placed on the market in accordance with [20-1a] );-food additives produced from maize MON810 that were authorised under Directive 89/107/EEC, and feed produced from maize MON810, i.e., feed additives lawfully placed on the market under Directive 70/524/EEC and feed materials (Reference EFSA-GMO-RX-MON810 [8-1b/20-1b] ).After the date of entry into force of the Regulation (EC) No 1829/2003, the products mentioned above were notified to the European Commission according to Articles 8 or 20 of this Regulation and subsequently included in the Community Register of GM food and feed.Maize MON810 expresses a Cry1Ab insecticidal protein, derived from Bacillus thuringiensis subsp. kurstaki, which confers protection against lepidopteran target pests such as the European corn borer (Ostrinia nubilalis) and species belonging to the genus Sesamia.In delivering its scientific opinion, the EFSA GMO The EFSA GMO Panel assessed maize MON810 with reference to the intended uses and appropriate principles described in the guidance document of the EFSA GMO Panel for the risk assessment of GM plants and derived food and feed. The scientific assessment included molecular characterisation of the inserted DNA and expression of target proteins. A comparative analysis of agronomic traits and composition was undertaken, and the safety of the new protein and the whole food/feed were evaluated with respect to potential toxicity, allergenicity and nutritional quality. An assessment of environmental impacts and the postmarket environmental monitoring plan were undertaken.Maize MON810 was generated by particle acceleration technology. Maize MON810 expresses a cry1Ab coding sequence that encodes an insecticidally active Cry1Ab protein. The molecular characterisation data established that a single insert is integrated in the maize The expression of the genes introduced by genetic modification has been su...

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Lack of detectable allergenicity of transgenic maize and soya samples

Cited by 60 publications

References 35 publications

Genetically Modified Foods and the Probable Risks on Human Health

Genetically Modified Foods and the Probable Risks on Human Health

Transgenic Residues in Soybean-based Foods

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