Lack of Correlation Between Transconjunctival O2 and Cerebral Blood Flow during Carotid Artery Occlusion

Gibson, Beth E.; McMichan, John C.; Cucchiara, Roy F.

doi:10.1097/00000542-198602000-00029

Cited by 13 publications

(3 citation statements)

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“…The need for a method to identify ongoing occult blood loss in trauma victims that is noninvasive, fast, accurate, and simple in the emergency of trauma victims, and logic response to blood loss Seen from animal to to use is apparenL2 Previously, noninvasive blood oxygenation measurements have been attempted. [25][26][27][28] The various weaknesses of these approaches have been summarized e l~e w h e r e .~~~~7 -~~ This study demonstrates the potential value of a device that uses spectrophotometric technology to evaluate 0, saturation in the large vessels of the eye. The rate of decrease in retinal venous 0, saturation seen in these animals was consistent and rate-dependent.…”

Section: Discussionmentioning

confidence: 99%

Retinal Venous Oxygen Saturation Correlates with Blood Volume

Denninghoff¹,

Smith

Hillman

et al. 1998

Academic Emergency Medicine

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I Abstract. Objectives: To evaluate the sensitivity of 1 retinal venous 0, saturation (SrvO,) for early blood ' loss and reinfusion. A secondary objective was to mea-~ sure the correlation between SrvO, and mixed venous 0, saturation (SvO,) during blood loss and reinfusion. Methods: Seven anesthetized swine were bled a t 0.8 mlflrglmin to 16 m m g . Shed blood was re-infused a t the same rate and the swine were allowed to equilibrate. After equilibration, repeat hemorrhages were performed at 1.6 ml/kg/min and 2.4 ml/kg/min. SrvO, was measured using a n eye oximeter (EOX) and SvO, was measured using a fiber-optic catheter. The retinal vasculature offers a potential site for noninvasive monitoring of perfusion Retinal perfusion has been used associated with cerebral perfusion under adverse conditions. 13-l5 Retinal vessel oximetry can detect changes in 0, saturation as small as +4%.10Js-18 In a study of large retinal vessel saturations, the retinal venous 0, saturation (SrvO,) In a pilot test of the device, swine were bled at a slow rate (0.4 ml/kg/min) to a modest end point (16 mL/kg).20 In the pilot study, there was a strong negative correlation between the amount of blood removed and SrvO, (r = -0.93). We also described

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Section: Discussionmentioning

confidence: 99%

Retinal Venous Oxygen Saturation Correlates with Blood Volume

Denninghoff¹,

Smith

Hillman

et al. 1998

Academic Emergency Medicine

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“…Previous studies in which the conjunctiva was used for intraoperative monitoring by measuring oxygen tension during carotid artery surgery did not directly visualize the microcirculation and yielded conflicting results. [13][14][15] Recently a new technology, ie, orthogonal polarized spectral (OPS) imaging, has been introduced, enabling noninvasive investigation and quantification of the human microcirculation in vivo 16 by placing a special camera at a distance of 0.5-1 mm to the surface of the target organ. Cross-polarization of the reflected green light results in hemoglobindependent contrast enhancement of vascular structures.…”

mentioning

confidence: 99%

Noninvasive analysis of conjunctival microcirculation during carotid artery surgery reveals microvascular evidence of collateral compensation and stenosis-dependent adaptation

Schaser¹,

Settmacher²,

Puhl³

et al. 2003

Journal of Vascular Surgery

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These results suggest adaptive mechanisms of capillary perfusion with increasing stenosis and development of collateral compensatory circulation in the vascular region of the human ICA. Conjunctival orthogonal polarized spectral imaging during unilateral ICA reconstruction enables continuous noninvasive analysis of bilateral conjunctival microcirculation in the terminal region of the ICA and enables monitoring for efficient carotid shunt perfusion during and after endarterectomy.

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“…[11] keine Beziehung zwischen der transkonjunktivalen Sauerstoffspannung und dem zerebralen Blutfluß (CBF), gemessen mittels Xenon, beschrieben werden. [11] keine Beziehung zwischen der transkonjunktivalen Sauerstoffspannung und dem zerebralen Blutfluß (CBF), gemessen mittels Xenon, beschrieben werden.…”

Section: Transkonjunktivaler Sauerstoffpartialdruck (Pcjo 2 )unclassified

Die Messung lokaler Sauerstoffparameter zur Detektion zerebraler Ischämien

et al. 2000

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During carotid endarterectomy the measurement of conjunctival oxygen tension is not useful to detect cerebral ischemia. The use of NIRS as a single neuronal monitor is not appropriate to perform, "selective shunting". In contrast to SEP, however, NIRS is characterized by its rapid changes immediately following carotid occlusion. This non invasive method is likely to complete the standard method SEP in a modified monitoring concept of neuronal function during carotid endarterectomy.

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Lack of Correlation Between Transconjunctival O2 and Cerebral Blood Flow during Carotid Artery Occlusion

Cited by 13 publications

References 0 publications

Retinal Venous Oxygen Saturation Correlates with Blood Volume

Retinal Venous Oxygen Saturation Correlates with Blood Volume

Noninvasive analysis of conjunctival microcirculation during carotid artery surgery reveals microvascular evidence of collateral compensation and stenosis-dependent adaptation

Die Messung lokaler Sauerstoffparameter zur Detektion zerebraler Ischämien

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