Abstract:In recent years, isothermal nucleic acid amplification techniques have been developed as alternatives to polymerase chain reaction (PCR) requiring thermal cycles. The integration of isothermal amplification into electrical or electrochemical devices realizes high throughput nucleic acid-based assays and confers high sensitivity. In this research, we tried to develop electrical/electrochemical biosensors detecting nucleic acids aiming at application to future liquid biopsy. For detection of small DNAs or microR… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.