Label-free liquid crystal immunosensor for detection of HBD-2

Su, Xiuxia; Huo, Wenjing; Yang, Dong; Luan, Chonglin; Xu, Jianling

doi:10.1016/j.talanta.2019.05.055

Cited by 28 publications

(9 citation statements)

References 34 publications

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“…1% APTMS solution was prepared in ethanol and IGZO TFT was immersed in it for 2 hours. On the other hand, Su et al 107 used a mixture of trimethoxysilyl chloride (DMOAP) and APTES SAMs for labelfree detection of HBD-2 (human b-defensin-2). In this work, glass slides were immersed in solution of 3% (v/v) APTES and 1% (v/v) DMOAP in ethanol at 80 1C for 2 hours.…”

Section: Self-assembled Monolayers In Biosensorsmentioning

confidence: 99%

The role of self-assembled monolayers in electronic devices

2020

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Section: Self-assembled Monolayers In Biosensorsmentioning

confidence: 99%

The role of self-assembled monolayers in electronic devices

2020

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“…Upon the specific binding between the anti-CB antibody and CB, or anti-HBD-2 antibody and HBD-2, the orientation of LC changed from homeotropic to tilted, increasing the brightness of the polarized optical image. This label-free detection method provided a low LOD for CB at 50 ng/mL and HBD-2 at 0.53 ng/mL, respectively [ 89 , 90 ]. In addition, Xia et al proposed an LC-based cardiac troponin I (cTnI) immunosensor.…”

Section: Applications In Lc Biochemical Sensorsmentioning

confidence: 99%

State-of-the-Art Development in Liquid Crystal Biochemical Sensors

et al. 2022

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As an emerging stimuli-responsive material, liquid crystal (LC) has attracted great attentions beyond display applications, especially in the area of biochemical sensors. Its high sensitivity and fast response to various biological or chemical analytes make it possible to fabricate a simple, real-time, label-free, and cost-effective LC-based detection platform. Advancements have been achieved in the development of LC-based sensors, both in fundamental research and practical applications. This paper briefly reviews the state-of-the-art research on LC sensors in the biochemical field, from basic properties of LC material to the detection mechanisms of LC sensors that are categorized into LC-solid, LC–aqueous, and LC droplet platforms. In addition, various analytes detected by LCs are presented as a proof of the application value, including metal ions, nucleic acids, proteins, glucose, and some toxic chemical substances. Furthermore, a machine-learning-assisted LC sensing platform is realized to provide a foundation for device intelligence and automatization. It is believed that a portable, convenient, and user-friendly LC-based biochemical sensing device will be achieved in the future.

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“…The pattern can be recorded and analyzed in order to infer the composition of the external material. Based on this characteristic, a variety of sensors based on LCs have been introduced ( Su et al, 2019 ; Hong and Jang 2020 ).…”

Section: Introductionmentioning

confidence: 99%