Label-free detection of H1N1 virus for point of care testing

Ultrasensitive Label-Free Immunoassay for Optical Determination of Amitriptyline and Related Tricyclic Antidepressants in Human Serum

“…Label-free immunoassays often suffer from unspecific binding by matrix components. For a better shielding, the transducer surface is coated with biopolymers, for example, functionalized dextran or polyethylene glycol. , In preliminary works, the two biopolymer coatings amino-dextran (AMD) and diamino-polyethylene glycol (DA-PEG) were tested and compared . Even though contact angle measurements revealed a higher NRT surface loading for AMD-coated transducers, DA-PEG-coated transducers show higher and foremost mass-transport-limited binding signals.…”

Real-time monitoring of nanomolar binding to a cyclodextrin monolayer immobilized on a Si/SiO2/novolac surface using white light reflectance spectroscopy: The case of triclosan

“…Sampling rates at several Hertz are possible. Also, the method is quite temperature insensitive since the thermal expansion of the layers is counteracted by the refractive index decrease with temperature, keeping in mind that the optical length is simply the product of the two factors [23].…”

Enhancing the sensitivity of a surface plasmon resonance-based optical sensor for zinc ion detection by the modification of a gold thin film

“… 2 Basically, optical sensors require a recognition element that can interact specifically with the desired target analytes and then, the sensor will detect the signal of the binding event. 3 For instance, reflection interference spectroscopy (RIFS), 4 surface-enhanced Raman scattering (SERS) spectroscopy, 5 and surface plasmon resonance (SPR) are optical sensors that require a recognition element. 6 SPR is one of the favorable optical sensors that is widely used in sensing biochemical reaction owing to its advantages such as low-cost, label-free, fast measurement, and simple sample preparation.…”