La constitution de l′acide hyaluronique. Sur les polysaccharides aminés III

Meyer, Kurt H.; Fellig, J.; Fischer, Ed. H.

doi:10.1002/hlca.19510340329

Cited by 24 publications

(1 citation statement)

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“…No separation was achieved when 4% of sodium borate was used in the place of the water in the mixture (4%, w/v, sodium borate-2-5 M-K2HPO4-2-methoxyethanol-33 % H3PO4; 1: 1: 1: 0-05, by vol. ), a result in agreement with the proposed structure for hyaluronic acid which contains no cis-diol groupings (Meyer, Fellig & Fischer, 1951;Jeanloz & Forchielli, 1951). Since Beale, Harris & Roe (1952) have shown that Rous-tumour RNA could be satisfactorily separated from hyaluronic acid by the use of hyaluronidase the investigation was not continued.…”

Section: B)supporting

confidence: 70%

A new method for the isolation of ribonucleic acids from mammalian tissues

Kirby

1956

Biochemical Journal

803

141

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1. A micro-organism identified as a species of Pweudomona8 forms adaptive enzymes which oxidize a large number of polyols. The properties and specificities ofthe enzymes have been studied in cell-free extracts. They are diphosphopyridine nucleotide-linked dehydrogenases converting polyols into ketoses.2. Sorbitol and dulcitol induce L.he formation of galactitol dehydrogenase, which oxidizes dulcitol to D-tagatose and accounts for the oxidation of other fully hydroxylated polyols containing an L-threo configuration adjacent to a primary alcohol group.3. Dulcitol also induces the formation of a less stable enzyme (D-iditol dehydrogenase) which accounts for the oxidation of certain fully hydroxylated polyols containing a D-threo configuration adjacent to a primary alcohol group.4. A labile mannitol dehydrogenase occurs in the extracts of cells grown in media supplemented with sorbitol.I am greatly indebted to Professor N. L. Edson for suggesting this problem and for his invaluable advice and criticism throughout the course of this work.

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Section: B)supporting

confidence: 70%