l-Tryptophan treatment and the episodic secretion of pituitary hormones and cortisol

Hyyppä, Markku T.; Jolma, Tapani; Liira, Juha; Långvik, Vivi-Ann; Kytömäki, O.

doi:10.1016/0306-4530(79)90038-6

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1981

1988

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Cited by 18 publications

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“…(37,42). Our own laboratory standards were used to adjust results from the CIS kit (17). The analyses were performed within three months of the sampling order to avoid possible destruction of PRL due to storing.…”

Section: Methodsmentioning

confidence: 99%

Prolactin Levels in Cerebrospinal Fluid of Patients with Chronic Schizophrenia

Rimón¹,

Liira²,

Kampman³

et al. 1981

Neuropsychobiology

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Baseline concentrations of prolactin (PRL) were determined in the CSF of 28 lobotomized and 28 non-lobotomized patients with chronic schizophrenia. The mean PRL level of the female patients was significantly higher than that of the male patients (p < 0.001). In addition, non-lobotomized patients had significantly higher concentrations of CSF PRL than patients of the lobotomized group (p < 0.05). On the other hand, patients belonging to the latter group exhibited significantly more central as well as cortical brain atrophy than the patients on whom no psychosurgery had been performed (0.05 > p < 0.001). The significance of cerebrospinal PRL as an index of central dopamine metabolism is discussed.

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Section: Methodsmentioning

confidence: 99%