“…The use of these tests assumes that the secretion of hypothalamic hormones is regulated in part by the activlty Gf central Furthermore, neuroendocrine markers may provide a useful approach to evaluate changes in receptor sens1t1vlty which have been suggested to be relevant in the neurobiology of psychiatrie disorders and to the mechanism of action of antidepressant drugs (Mueller et al 1985;Stahl, 1992;Yatham and Steiner, 1993). To date, 5-HT precursors, releasing agents, reuptake inhibltors, receptor agonists and antagonists have aIl been used as probes in neuroendocrtne tests to study 5-HT function…”