L-Norvalin and Ischemical Preconditioning Action Mechanisms Analysis at Liver Ischemia/Reperfusion

Abstract

In this article ischemical preconditioning and L-norvalin efficacy and mechanisms of action pharmacological analysis at liver experimental ischemia/reperfusion were made. During investigation ischemical preconditioning high effectiveness totally wasn’t blocked by glibenclamide showed. L-norvaline also showed marked hepatoprotective effect abolished by glibenclamide just partly.

Pharmacological Efficiency of Statins and L-Norvalin at an Endotoxin-Induced Endothelial Dysfunction

“…The vascular endothelial is a place for realization of normal and pathological immune and biochemical reactions proceeding with participation of mediators of inflammatory reaction, nitrogen oxide and its metabolites, active radicals of oxygen, etc. at the endotoxin-induced endothelial dysfunction (EIED) [4,5,6,7,8,9,10].…”