Knowledge, Attitude and Practice of Genotype Screening Among Undergraduate Students of the University of Abuja, Nigeria

Yalma, Ramsey Msheliza; Awodiji, Mary Mayowa

doi:10.11648/j.ejpm.20210902.16

Cited by 2 publications

(1 citation statement)

References 18 publications

(27 reference statements)

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“…[50][51][52] On the contrary, several studies revealed adequate knowledge of sickle cell disease, genetic counselling, and haemoglobin genotyping with positive preventive practices and attitudes towards the condition. Significant knowledge of the causes, signs, and symptoms of sickle cell disease with positive preventive practices towards the condition was reported among students of tertiary institutions [53][54][55] and youths in Yaba, Nigeria. 56,57 Oluwole and Adeyemo 58 reported high levels of awareness, good knowledge, and positive attitudes towards sickle cell disease.…”

Section: Knowledge About Sickle Cell Diseasementioning

confidence: 99%

A Critical Review of Sickle Cell Disease Burden and Challenges in Sub-Saharan Africa

Adigwe¹,

Onoja²,

Onavbavba³

2023

JBM

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Sickle cell disease is caused by an abnormality of the β-globin gene and is characterised by sickling of the red blood cells. Globally, sub-Saharan African countries share the highest burden of the disease. This study aimed at critically reviewing studies focusing on challenges of sickle cell anaemia in sub-Saharan Africa. A literature search was carried out in five major databases. Articles that met the inclusion criteria were included in the bibliometric review and critical analysis. A majority of the studies were undertaken in the West African region (85.5%), followed by Central Africa (9.1%). Very few studies had been undertaken in East Africa (3.6%), whilst the Southern African region had the fewest studies (1.8%). Distribution in relation to country revealed that three quarters of the studies were carried out in Nigeria (74.5%), followed by the Democratic Republic of the Congo (9.1%). According to healthcare settings, a strong majority of the studies were undertaken in tertiary health care facilities (92.7%). Major themes that emerged from the review include interventions, cost of treatment, and knowledge about sickle cell disease. Public health awareness and promotion as well as improving the quality of sickle cell centers for prompt management of patients with sickle cell disorder was identified as a critical strategy towards reducing the burden of the disease in sub-Saharan Africa. To achieve this, governments in countries located in this region need to adopt a proactive strategy in addressing gaps that have been identified in this study, as well as instituting other relevant measures, such as continuous media engagement and public health interventions relating to genetic counselling. Reforms in other areas that can help reduce the disease burden, include training of practitioners and equipping sickle cell disease treatment centers according to World Health Organization specifications.

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Section: Knowledge About Sickle Cell Diseasementioning

confidence: 99%

A Critical Review of Sickle Cell Disease Burden and Challenges in Sub-Saharan Africa

Adigwe¹,

Onoja²,

Onavbavba³

2023

JBM

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Knowledge and awareness of sickle cell disease: a cross sectional study amongst unmarried adults in Nigeria’s capital city

Adigwe

2022

J Community Genet

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Sickle cell disease is a genetic disorder characterised by the tendency of haemoglobin to polymerise and deform red blood cells to a sickle or crescent shape; this consequently results in vaso-occlusive condition. A better knowledge and awareness about sickle cell disease amongst the population can help reduce its prevalence. This study aimed at assessing awareness and knowledge of unmarried adults in Nigeria’s capital. A cross sectional survey was undertaken amongst unmarried individuals residing in the Federal Capital Territory. Questionnaires were administered to participants using convenience sampling strategy. Data were analysed using Statistical Package for Social Sciences version 25. Descriptive and inferential statistical analyses were carried out. A total of 1423 questionnaires were completed and returned, response rate was 83.71%, male participants were in the majority as indicated by 52% of the sample, and the dominant age group was 21 to 30 years (47.90%). Almost all the study participants (92.50%), have heard about sickle cell disease. Knowledge about sickle cell disease was average, as mean score for all the participants was 9.01 ± 3.18, with a range of 0 to 17. Some misconceptions were observed, for instance some participants believed that bacterial or viral infections could cause sickle cell disease. Male participants had a higher knowledge score compared to females (p < 0.001), and older participants were more knowledgeable about sickle cell disease (p < 0.001). This study identified that knowledge gaps exist about sickle cell disease. Emergent findings can underpin government, policymakers’ and stakeholders’ contextual strategies to prevent sickle cell through public health enlightenment and other relevant means.

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Knowledge, Attitude and Practice of Genotype Screening Among Undergraduate Students of the University of Abuja, Nigeria

Cited by 2 publications

References 18 publications

A Critical Review of Sickle Cell Disease Burden and Challenges in Sub-Saharan Africa

A Critical Review of Sickle Cell Disease Burden and Challenges in Sub-Saharan Africa

Knowledge and awareness of sickle cell disease: a cross sectional study amongst unmarried adults in Nigeria’s capital city

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