Knee arthoplasty in obese patients

Helo, M. J.; Ахтямов, И. Ф.; Саид, Ф М; Gilmutdinov, I. Sh.; Файзрахманова, Г М

doi:10.32000/2072-1757-2018-7-94-97

Cited by 3 publications

(2 citation statements)

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“…Osteoarthritis (OA) is a chronic degenerative-inflammatory disease in which the articular cartilage, subchondral bone, synovial membrane, ligaments, capsule and periarticular muscles are affected (Kraus et al 2015;Grässel and Muschter 2020 ). According to various sources, OA can occur in 6 to 30% of people (Mustafin and Khusnutdinova 2015;Helo et al 2018;Ariani et al 2019) and is more often observed in people over 40-50 years old (Palazzo et al 2016). Total arthroplasty is the most effective treatment for terminal OA (Helo et al 2018).…”

Section: Introductionmentioning

confidence: 99%

“…According to various sources, OA can occur in 6 to 30% of people (Mustafin and Khusnutdinova 2015;Helo et al 2018;Ariani et al 2019) and is more often observed in people over 40-50 years old (Palazzo et al 2016). Total arthroplasty is the most effective treatment for terminal OA (Helo et al 2018). All over the world, there is a tendency for an increase in the number of surgeries for endoprosthetics of large joints of the lower extremities (Oremus 2015;Leitner et al 2018).…”

Section: Introductionmentioning

confidence: 99%

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Development of a risk-oriented algorithm for the combined use of hemostatics and anticoagulants to prevent thrombosis and bleeding cases after total arthroplasty of knee or hip joints

Головко¹,

Сафроненко²,

Gantsgorn³

et al. 2021

RRP

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Introduction: The goal of our study was to develop a risk-oriented algorithm for the combined use of hemostatics and anticoagulants in patients after total arthroplasty of the knee or hip joints to reduce the risk of thrombohemorrhagic complications. Materials and methods: We performed a retrospective study (n=253). In group (Gr.) 1, the time interval (TI) between the administration of hemostatic and anticoagulant prophylaxis was ≤17 hours (n=145; 57.31%), and in Gr. 2 – 18-24 hours (n=108; 42.68%). We analyzed the influence of different factors on the development of thrombosis and bleeding cases after the operation. Results and discussion: Thrombohemorrhagic complications were observed in 27 (10.67%) patients. Thrombosis in Gr. 1 was associated with the use of tranexamic acid, and were recorded 2.2 times more often than in Gr. 2 (p<0.05). The development of thrombosis in Gr. 1 was influenced by: class II obesity, type 2 diabetes mellitus, myocardial infarction, venous pathology, age of patients >75 years, for women – an initially low level of international normalized ratio, and activated partial thromboplastin time (APTT) (p<0.05). The development of bleeding in Gr. 1 was influenced by: age >75 years, among men and women – an increased preoperative level of APTT, for women – a decreased level of fibrinogen and platelets (p<0.05). Conclusion: To prevent thrombosis and bleeding after arthroplasty of large joints, the TI between the use of hemostatics and anticoagulants should be at least 18 hours, especially in patients with the above risk factors, in particular, when using tranexamic acid and low molecular weight heparins.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development of a risk-oriented algorithm for the combined use of hemostatics and anticoagulants to prevent thrombosis and bleeding cases after total arthroplasty of knee or hip joints

Головко¹,

Сафроненко²,

Gantsgorn³

et al. 2021

RRP

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Interstitial electrical stimulation for middle-aged, and elderly adults with early stages of knee osteoarthritis

Burmatov,

Sergeev,

Luneva

et al. 2024

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Introduction The adequate, pathogenetically substantiated pain management is essential for treatment of early stages of deforming osteoarthritis of the knee joint. There is a need to explore the effectiveness and mechanisms of modern methods of electrical therapy and their impact on the quality of life due to close cause-and-effect relationship between the pain, inflammatory and destructive components of osteoarthritis (OA) as one of the most common conditions.The objective was to evaluate the effect of interstitial electrical stimulation (IES) as a monotherapy in the course of conservative treatment of early stages of gonarthrosis based on clinical and biochemical findings.Materials and methods Radiographic findings, skin electrometry (objective parameters of pain intensity), limb weight-bearing capacity, biochemical parameters of connective tissue matrix degradation in blood serum and 24-hour urine samples, and treatment satisfaction were explored in 43 patients. Patients who received a course of IES were assigned to the treatment group (n = 22) and patients who received standard treatment without IES constituted the control group (n = 21).Results Electrometric analysis showed a higher effectiveness of pain relief in the treatment group compared to the controls with asymmetry coefficient measuring 3.2 ± 0.31 versus 1.9 ± 0.4 at p > 0.05. The weight‑bearing scored 3.59 ± 0.34 versus 3.26 ± 0.2 at p > 0.05. The treatment group showed shorter treatment length with 13.21 ± 1.2 days versus 18.3 ± 1.2 days in the control group at p > 0.05 and a higher degree of satisfaction with outcomes scored 96.2 ± 2.59 in the treatment group versus 86.2 ± 3.17 in the control group. A statistically significant difference (p > 0.05) was established in the levels of free and total hydroxyproline characterizing the different intensity of collagen breakdown in the groups at the end of treatment.Discussion The IES used as an analgesic and anti-inflammatory therapy was shown to be highly effective with changes in the hydroxyproline level in the media suggesting a chondroprotective effect. The analysis and comparison of objective parameters demonstrated high effectiveness of IES in the treatment of early stages of gonarthrosis in middle-aged and elderly adults.Conclusion The IES used for treatment of early stages of gonarthrosis helps pain reducing the intensity of collagen destruction and improving weight-bearing.

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Impact of the Initial Coagulation Parameters and the Time Interval between Hemostatics and Anti coagulants on the Risk of Thrombohemorrhagic Complications After Endoprosthetics of Large Joints

et al. 2021

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The article confirms the significance of the time interval of at least 18 hours between the hemostatic and anticoagulant therapy, which is of particular importance when tranexamic acid is used. An analysis of the thrombohemorrhagic complications developed in the early postoperative period after arthroplasty of large joints of the lower extremities was carried out. In addition, the most significant coagulation parameters were determined, whose deviation from the norm before surgery increased the risk of thrombosis and bleeding after joint replacement among male and female patients.

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Knee arthoplasty in obese patients

Cited by 3 publications

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Development of a risk-oriented algorithm for the combined use of hemostatics and anticoagulants to prevent thrombosis and bleeding cases after total arthroplasty of knee or hip joints

Development of a risk-oriented algorithm for the combined use of hemostatics and anticoagulants to prevent thrombosis and bleeding cases after total arthroplasty of knee or hip joints

Interstitial electrical stimulation for middle-aged, and elderly adults with early stages of knee osteoarthritis

Impact of the Initial Coagulation Parameters and the Time Interval between Hemostatics and Anti coagulants on the Risk of Thrombohemorrhagic Complications After Endoprosthetics of Large Joints

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