Impact of the Initial Coagulation Parameters and the Time Interval between Hemostatics and Anti coagulants on the Risk of Thrombohemorrhagic Complications After Endoprosthetics of Large Joints

Abstract

The article confirms the significance of the time interval of at least 18 hours between the hemostatic and anticoagulant therapy, which is of particular importance when tranexamic acid is used. An analysis of the thrombohemorrhagic complications developed in the early postoperative period after arthroplasty of large joints of the lower extremities was carried out. In addition, the most significant coagulation parameters were determined, whose deviation from the norm before surgery increased the risk of thrombosis and bleeding after joint replacement among male and female patients.