Kluyvera Infections in the Pediatric Population

Carter, J Elliot; Laurini, Javier A.; Mizell, Kelly N.

doi:10.1097/inf.0b013e318170af5b

Cited by 12 publications

(5 citation statements)

References 16 publications

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“…It has been reported that three (K. ascorbata, K. cryocrescens, K.georgiana) of the four types demonstrated until the present time cause infection in humans and the most common among these is K. ascorbata as in our patient series (8). While K. ascorbata was isolated in 11 of 19 pediatric patients in the literature and K. cryocrescens was isolated in three, typing could not be done in five (3)(4)(5)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). In Table 1, all pediatric cases in which Kluyvera infection was reported is summarized.…”

Section: Discussionmentioning

confidence: 70%

Kluyvera ascorbata infections in children: a case series

et al. 2015

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Kluyvera is a relatively newly described member of the Enterobacteriaceae family that rarely causes infections in humans. In the pediatric population, it is described in association with clinically significant infections ranging from urinary tract infections to sepsis with multiorgan failure. Our aim is to determine the clinical significance of K. ascorbata infections in the pediatric population at our institution. We retrospectively analyzed clinical microbiology data as from 2006 and identified four clinically significant isolates in this period. The isolates were from four cases who presented with sepsis, bacteremia associated with central venous catheter, pyelonephritis and intraabdominal collection. The ages of these patients ranged between seven months to 17 years. All patients received prompt antimicrobial treatment on the basis of susceptibility testing and good clinical response was obtained in all patients. Successful treatment options include third-generation cephalosporins, aminoglycosides, betalactams with beta-lactamase inhibitors and carbapenems. Clinicians should be aware of the spectrum of disease and increasing clinical importance associated with this pathogen. (Turk Pediatri Ars 2015; 50: 123-8)

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Section: Discussionmentioning

confidence: 70%

Kluyvera ascorbata infections in children: a case series

et al. 2015

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“…In humans, it is part of the normal flora of the digestive tract. Kluyvera infection is rare but has increasingly been reported [5], such as in children [6].…”

Section: Discussionmentioning

confidence: 99%

A case of urinary tract infection caused by Kluyvera ascorbata in an infant: case report and review of the literature

Isozaki

Shirai

Mimura

et al. 2010

Journal of Infection and Chemotherapy

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“…Kluyvera ascorbata has been implicated as an opportunistic pathogen in neonates . Therefore, to reduce neonatal morbidity and mortality, prompt identification of Kluyvera as the causative agent and use of appropriate antibiotics are mandatory.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, Kluyvera has been associated with clinically significant infections such as urinary tract infection (UTI), bacteremia, and severe sepsis . Of the 15 clinically significant cases of pediatric Kluyvera infection, three cases of fatal infection have been documented, but only a few neonatal cases of Kluyvera infection have been reported …”

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confidence: 99%