Klonale Evolution im Spätstadium der chronischen myeloischen Leukämie

Bauke, J

doi:10.1055/s-0028-1107167

Cited by 6 publications

(3 citation statements)

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“…It is suggestive that the same combination of 2 Ph' and i(17q) without trisomy No. 8 appears to be lacking in 8 cases with 2 Phl and 8 cases with i(17q) of Bauke (1973), as well as in 20 cases from the literature tabulated by Bauke (19731, and in the i(17q)positive cases of Grouchy and Turleau (1974).…”

Section: Resultsmentioning

confidence: 84%

“…All chromosome changes reported in the remaining 67 cases, including the 10 described in this paper, are listed in Table TI. It is striking that Bauke (1973), as well as in 20 cases from the literature tabulated by Bauke (19731, and in the i(17q)-positive cases of Grouchy and Turleau (1974).…”

Section: Resultsmentioning

confidence: 90%

“…13. Several authors have provided evidence for a corresponding sequence of stepwise karyotypic changes in CML (Ford and Clarke, 1963;Grouchy et a/., 1966;Bauke, 1973).…”

Section: Resultsmentioning

confidence: 99%

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Non‐random karyotypic evolution in chronic myeloid leukemia

Mitelman

Levan

Nilsson

et al. 1976

Intl Journal of Cancer

134

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The chromosome banding pattern was analyzed in bone-marrow cells and/or spleen cells of 10 patients in the blastic phase of chronic myeloid leukemia (CML). It was obvious from the karyotype analysis that the chromosome aberrations occurring addition to the Philadelphia chromosome (Ph1) were strictly non-random. An extra Ph1, trisomy 8 and/or trisomy for the long arm of chromosome 17 were observed in all cases. This consistent pattern of chromosome involvement in CML was confirmed in 57 cases from the literature studied with banding techniques. In 88% of the total number of cases with further changes at least one of the three main chromosomal aberrations was found ("major route" of karyotypic evolution).

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Section: Resultsmentioning

confidence: 84%

Section: Resultsmentioning

confidence: 90%