Klinische Bedeutung der Antibiotikaresistenz in Gynäkologie und Geburtshilfe

Aims: We aimed to examine the association of cognitive decline with quality of life (QoL) in dementia compared to controls and to determine variables associated with QoL. Methods: Every subject was placed within a specific group depending on their designation by the Mini Mental State Examination and evaluated by the Alzheimer’s Disease Related Quality of Life (ADRQL) and clinical assessments. Results: QoL for the mild dementia group was lower (p = 0.08) than that of controls. The very severe dementia group had a significantly lower QoL than the other dementia groups, which all had similar ADRQL scores. The only predictor of ADRQL scores was found to be the behavioral and psychological symptoms of dementia. Conclusion: There is no direct relationship between cognitive decline and QoL.

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Prevalence and Treatment of Neuropsychiatric Symptoms in Advanced Dementia

Kverno¹,

Rabins²,

Blass³

et al. 2008

J Gerontol Nurs

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Neuropsychiatric symptoms (NPS) are common in dementia, although little is known about their prevalence and treatment near the end of life. This study used a retrospective review of the medical records of 123 hospice-eligible nursing home residents with advanced dementia to investigate the prevalence of NPS and NPS-targeted pharmacological and non-pharmacological treatments. The most prevalent NPS were agitation or aggression (50.4%), depression (45.5%), and withdrawal/lethargy (43.1%). Of the 105 (85.4%) residents who exhibited one or more NPS, 90.5% were receiving at least one NPS-targeted treatment, yet 41.9%, received no documented non-pharmacological NPS-targeted care. The majority of documented non-pharmacological care focused on safety and explanations or instructions given to residents. Given the high prevalence of co-morbidities, associated risks for medication interactions or serious side effects, and potential low-risk benefits of psycho-behavioral care, these findings raise concerns about how to best increase the provision and documentation of non-pharmacological care in advanced dementia.

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Klinische Bedeutung der Antibiotikaresistenz in Gynäkologie und Geburtshilfe

Cited by 4 publications

References 109 publications

Lactobacillus johnsonii HY7042 ameliorates Gardnerella vaginalis-induced vaginosis by killing Gardnerella vaginalis and inhibiting NF-κB activation

Lactobacillus johnsonii HY7042 ameliorates Gardnerella vaginalis-induced vaginosis by killing Gardnerella vaginalis and inhibiting NF-κB activation

Relationship between Quality of Life and Cognitive Decline in Dementia

Prevalence and Treatment of Neuropsychiatric Symptoms in Advanced Dementia

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