1979
DOI: 10.1007/978-3-642-67301-6_2
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Kininogenases of Blood Cells (Alternate Kinin Generating Systems)

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Cited by 9 publications
(4 citation statements)
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“…Previous studies have shown that polymorphonuclear (PMN) leucocytes contain two distinct types of kininogenases (Greenbaum & Kim, 1967: Greenbaum et (11, 1969Greenbaum, , 1979Melmon & Cline, 1967;Movat et al, 1976;Newballetal, 1975;Lupkeetal, 1982). Oneisafamily of neutral proteases that catalyse the formation of methionyllysyl-bradykinin or bradykinin from plasma kininogen (Melmon & Cline, 1967;Movat et al, 1973Movat et al, , 1976Newball et al, 1975;Lupke et al, 1982).…”
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confidence: 99%
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“…Previous studies have shown that polymorphonuclear (PMN) leucocytes contain two distinct types of kininogenases (Greenbaum & Kim, 1967: Greenbaum et (11, 1969Greenbaum, , 1979Melmon & Cline, 1967;Movat et al, 1976;Newballetal, 1975;Lupkeetal, 1982). Oneisafamily of neutral proteases that catalyse the formation of methionyllysyl-bradykinin or bradykinin from plasma kininogen (Melmon & Cline, 1967;Movat et al, 1973Movat et al, , 1976Newball et al, 1975;Lupke et al, 1982).…”
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confidence: 99%
“…Oneisafamily of neutral proteases that catalyse the formation of methionyllysyl-bradykinin or bradykinin from plasma kininogen (Melmon & Cline, 1967;Movat et al, 1973Movat et al, , 1976Newball et al, 1975;Lupke et al, 1982). The second group consists of the leucokinin-forming enzyme, which shows properties similar to cathepsins (Greenbaum, 1979); they act on leucokininogen to produce leucokinins, bioactive peptides of 2 1-25 amino acids (Chang et al, 1972;Freer et al, 1972). A further distinction between the two types of kininogenases is that leucokininogen and leucokinins are structurally distinct from plasma kininogens and kinins respectively (Greenbaum, , 1979.…”
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“…Besides kallikreins, neutrophils contain a number of other enzymes which are stored intracellulary in cytoplasmic granules. These enzymes, similarly to tissue kallikreins, have the capacity to generate kinins from kininogens (Movat et al ., 1973; Greenbaum, 1979; Lupke et al ., 1982) and may be implicated in the inflammatory responses.…”
Section: Discussionmentioning
confidence: 99%