Kinetics Studies of Oxidation of Furosemide by Acidic Potassium Permanganate

Abstract

The Kinetic of oxidation of Furosemideby potassium permanganate has been studied in the presence of acidic medium. The reaction is first order with respect to KMnO 4 as well as Furosemideconcentration. The reaction rate has been determined at different temperature and different thermodynamic parameters have been calculated which shows that the reaction rate increase with increase in temperature. With increase in the concentration of acid the reaction rate increases. A suitable mechanism has been proposed.