Kinetic study and modeling of the Schotten–Baumann synthesis of peroxyesters using phase-transfer catalysts in a capillary microreactor

Abstract

The kinetics of the synthesis of tert-butyl peroxy-2-ethylhexanoate were investigated in a capillary microreactor. TBPEH was synthesized from 2-ethylhexanoyl chloride and tert-butyl hydroperoxide in the presence of a strong base,...

Multi-objective Bayesian optimisation using q-noisy expected hypervolume improvement (qNEHVI) for the Schotten–Baumann reaction

“…When well-designed, a continuous flow allows precise control of reaction time, temperature, and can achieve good mixing and heat transfer. 6 Although the reaction itself is well-known, there are very few examples of performing the reaction in a flow, 7 and there are no studies exploring process parameters to propose a robust experimental protocol.…”

A kinetic model of the cycloaddition reactions between cyclopentadiene and 1,3‐butadiene for synthesis of 5‐vinyl‐2‐norbornene

“…Tubular reactors and micro-reactors are widely used in reaction mechanism research due to their realtime operation and excellent heat and mass transfer capabilities. [7][8][9][10] At room temperature (around 25 C), cyclopentadiene (CPD) tends to dimerize and becomes enriched in dicyclopentadiene (DCPD). [11] Therefore, the production process of VNB is divided into two main steps: thermal decomposition (the reverse Diels-Alder reaction) of DCPD into CPD, [12] and the Diels-Alder reaction between CPD and 1,3-butadiene (BD).…”

“…Tubular reactors and micro‐reactors are widely used in reaction mechanism research due to their real‐time operation and excellent heat and mass transfer capabilities. [ 7–10 ]…”

Homogeneous continuous-flow nitration of O-methylisouronium sulfate and its optimization by kinetic modeling

“…In recent years, continuous flow microreactors have been recognized due to their excellent mass and heat transfer performance, precise control over reaction parameters, and intrinsic safety. [5][6][7][8] Guo et al constructed a continuous flow microsystem for oxylene nitrification and proved the process safety of o-xylene nitrification by the adiabatic temperature rise of the nitrification reaction and the characteristic heat transfer time of the microreactor. [9] The residence time of the microreactor was reduced by an order of magnitude and the volumetric mass transfer coefficient was increased by several orders of magnitude compared with that of a conventional stirred tank reactors.…”