The present study introduced a new motion analysis method for total hip arthroplasty (THA). A motion simulation module of THA was designed and developed, which can simulate the THA's implantation condition and motion and detect the theoretic range of motion (ROM) before the prosthetic component impingement happens. The impingement risk of THA should be investigated through comparing the analysis data of module with the realistic kinematics obtained from hip motion measurement. Furthermore, in order to demonstrate how to use this module, the kinematic data of the hip were recorded by measuring the lower limbs motion of general population in six activities of daily living (ADLs), i.e., kneeling, squatting, ascending stair, descending stair, walking, and jogging. Analysis results showed that the possibilities of impingement and dislocation were larger during the squatting activity. It is reasonable to believe that the motion simulation module of THA in the present study is helpful for clinical medicine engineering, and hip implant design and optimization.Impingement has presented a high occurrence rate since THA has been wildly applied in clinic, and does great harm to patients (Yoshimine and Ginbayashi, 2002;Brown and Callaghan, 2008;Kessler et al., 2008;Tanino et al., 2008;Patel et al., 2010). The study on the subjects of the impingement and dislocation of THA has attracted scientists and doctors' attention. There are various factors that increase the propensity of impingement or dislocation; except the patients themselves, factors that we cannot choose, the clinical factor and hip implant design are the main factors. In the clinical factor, inappropriate selection of the implant option has a great chance to lead to cup/neck impingement or dislocation. As well, poor alignment of implants for individual patient also leads to serious consequences which depend on three implantation parameters: femoral anteversion, acetabular anteversion, and acetabular inclination (Ji et al., 2010). In implant design, impingement is also related with four design parameters: neck design, head-neck ratio, stem-neck angle, and cup opening plane design (Ji et al., 2010). In fact, these major factors are in direct linkage with human lower limb activity. If the realistic hip motion requirement of some activities is far more than the theoretic ROM provided by THA, then cup/neck impingement or dislocation will be bound to occur.In the present study, we used a 3D parameterized motion simulation module of THA to investigate THA's motion performance and impingement risk. All the implantation and design parameters mathematically influencing the theoretical ROM were involved. The module can easily imitate the implant environment of THA, simulate the motions of implants, and detect the maximum ROM before the cup/neck impingement happens. Furthermore, in order to demonstrate how to use this module, the