Kimura's disease of the epiglottis

Cho, M.S.; Kim, E.S.; Kim, H.J.; Yang, Wonjun

doi:10.1046/j.1365-2559.1997.5480804.x

Cited by 20 publications

(18 citation statements)

References 2 publications

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“…Involvement of the epiglottis is very unusual and probably a very rare occurrence. Similar to our case, Cho et al reported one case of KD presenting as an obstructing mass of the epiglottis in a young Asian male [10]. Occurrence of KD in the epiglottis can impose a challenging diagnostic workup for both clinicians and pathologists.…”

Section: Discussionsupporting

confidence: 84%

“…Even though, KD is mostly a head and neck lesion, few cases were reported in other locations e.g. axilla, trunk and groin [1,9,10]. Involvement of the epiglottis is very unusual and probably a very rare occurrence.…”

Section: Discussionmentioning

confidence: 99%

“…Knowledge of the presence of peripheral esinophilia should guide the clinician to the possibility of KD [4,10]. The final diagnosis is usually established with histological examination.…”

Section: Discussionmentioning

confidence: 99%

“…A very important histological differential diagnosis and pitfall to be avoided is ALHE. The important and helpful features differentiating KD from ALHE are summarized in (Table 2) [5,[7][8][9][10][11][12]. CD has characteristic ''onion-skin'' layering of the mantle zone with hyalinized blood vessels in the germinal centers.…”

Section: Discussionmentioning

confidence: 99%

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Kimura Disease of the Epiglottis

AbdullGaffar

Abdul-Haleem

Carlsen

2008

Head and Neck Pathol

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Kimura disease is a distinct clinicopathological entity of a benign chronic inflammatory disorder of unknown etiology. It is endemic in Oriental Asians, but sporadic and relatively rare in the West, both in whites and blacks alike. It usually presents as a mass lesion, most commonly in the head and neck region. It had for a long time been confused as synonymous with angiolymphoid hyperplasia with esinophilia. It can impose a challenging diagnosis both clinically and pathologically, especially in non-endemic areas with unusual sites involvement. Even though it is a benign lesion, it can be life-threatening in the epiglottis with a risk of airways obstruction. So far, one case had been reported in the epiglottis with upper respiratory tract obstruction. We report a similar case with a brief review of the literature.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

“…Knowledge of the presence of peripheral esinophilia should guide the clinician to the possibility of KD [4,10]. The final diagnosis is usually established with histological examination.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Kimura Disease of the Epiglottis

AbdullGaffar

Abdul-Haleem

Carlsen

2008

Head and Neck Pathol

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“…Other sites such as the oral cavity, axilla, groin, limbs, and trunk have also been described, but the involvement of the respiratory tract is rare. To our knowledge, 10 cases of KD centered around the epiglottis have appeared in the English and Japanese literature [7][8][9][10][11][12][13][14][15][16]. Our case provides an additional example (Table 1).…”

Section: Discussionmentioning

confidence: 85%

Kimura Disease of the Epiglottis: A Case Report and Review of Literature

Yamamoto

Minamiguchi

Watanabe

et al. 2013

Head and Neck Pathol

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Kimura disease (KD) affecting an unusual site is a diagnostic challenge. We report herein the case of a 62-yearold Japanese woman who presented with swelling of the epiglottis, resulting in airway narrowing. Microscopically, biopsied and resected specimens both revealed lymphoid proliferation of a reactive immunophenotype, accompanied by vascular proliferation, eosinophilic infiltration, and stromal sclerosis. Adjunctive immunohistochemistry with immunoglobulin E in addition to laboratory and histological findings led us to seriously consider a diagnosis of KD. The patient underwent surgical removal with postoperative steroid therapy and has no evidence of recurrence. Our experience suggests that KD is potentially fatal as well as showing difficulty in the histological diagnosis when occurring in the upper respiratory tract, such as the epiglottis. A literature review disclosed that our case is the 11th case so far reported in this location, and that KD of the epiglottis did not show any male preponderance, as seen in other places.

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Larynx and Hypopharynx

Gale

Cardesa

Zidar

Pathology of the Head and Neck

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Kimura's disease of the epiglottis

Cited by 20 publications

References 2 publications

Kimura Disease of the Epiglottis

Kimura Disease of the Epiglottis

Kimura Disease of the Epiglottis: A Case Report and Review of Literature

Larynx and Hypopharynx

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