2014
DOI: 10.1097/rhu.0000000000000064
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Kimura Disease Complicated With Bowel Infarction and Multiple Arterial Thromboses in the Extremities

Abstract: Kimura disease (KD) is a chronic inflammatory disease characterized by slowly growing subcutaneous nodules in the face and the neck region. Although a concomitant hypercoagulable state can accompany KD, massive thromboses in patients with KD have rarely been reported. Here, we report a case of KD complicated with bowel infarction and multiple arterial thromboses in the upper and lower extremities. The patient underwent bowel resection and was successfully treated with corticosteroid and anticoagulation.

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Cited by 11 publications
(6 citation statements)
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“…The main treatment for Kimura's disease is surgical removal of the mass and pathological examination, and continue treatment after surgery. According to previous literature, there are hormone therapy, radiotherapy, immunotherapy and treatment of ischemic vascular reconstruction (14,15). For those masses that cannot be completely removed, postoperative radiotherapy is more important.…”
Section: Discussionmentioning
confidence: 99%
“…The main treatment for Kimura's disease is surgical removal of the mass and pathological examination, and continue treatment after surgery. According to previous literature, there are hormone therapy, radiotherapy, immunotherapy and treatment of ischemic vascular reconstruction (14,15). For those masses that cannot be completely removed, postoperative radiotherapy is more important.…”
Section: Discussionmentioning
confidence: 99%
“…However, the increased serum IgE level and eosinophilia suggest an allergic disease [1–4]. Despite an unclear mechanism, hypereosinophilia can lead to a hypercoagulable condition and vasculitis according to some published reports [57]. A possible mechanism is that the cytokines secreted by eosinophils, including eosinophil cationic protein, eosinophil peroxidase, and major basic protein, activate platelet aggregation.…”
Section: Discussionmentioning
confidence: 99%
“…However, KD has been treated with local mass excision, steroids for systemic inflammation, revascularization, and anticoagulation for organ ischemia [1,2,5]. Some researchers have reported that radiotherapy was a successful treatment for KD [4].…”
Section: Discussionmentioning
confidence: 99%
“…Renal disease, nephrotic syndrome in particular, is present in up to 20% of patients with Kimura's disease [7]. Less commonly, several reports in the literature have linked Kimura's disease with a hypercoagulable state without associated nephrotic syndrome [8]. Less frequently, the orbit including the eyelids, conjunctiva, and lacrimal glands, paranasal sinuses, epiglottis, tympanic membrane, parotid gland, and parapharyngeal space may be involved [9][10][11].…”
Section: Discussionmentioning
confidence: 99%