Ketapang Leaf (Terminalia Catappa L.) Metabolite Profiling with Aquadest Fraction Ethanol Extract Using UPLC-MS

Abstract

Ketapang leaves (Terminalia catappa L.) are known for its traditional medicinal function. Ketapang leaves contain saponins, alkaloids, tannins, flavonoids, and triterpenoids. In general, polar solvent can increase the production of Ketapang leaves’ active compound. Utilization of a plant as herbal medicine is based on the presence of chemical compounds that have certain pharmacological effects. Therefore, metabolite profiling is needed. This is intended to understand the chemical compounds of Ketapang leaves. The objective of this study is to analyze the metabolite profile of chemical compounds and major compounds contained in the aquadest fraction ethanol extract using the UPLC-MS instrument. The results of the interpretation of the analysis of the compound content using UPLC-MS showed that there are 19 compounds in the ethanol extract of the aquadest fraction of Ketapang leaves. The major compound in the ethanol extract of the aqueous fraction of Ketapang leaves is Pelargonidin 3-O-glucoside with an iFit percentage of 97.56%.