Keratocystic odontogenic tumor: a retrospective study of 183 cases

Abstract

Aim: The purpose of this retrospective study was to evaluate the clinicopathological features of 64 patients with keratocystic odontogenic tumor (KCOT). Materials and Methods: The patients ranged in age at the time of diagnosis from 8 to 74 years (mean: 38.20 ± 16.71). Postoperative follow-up period was 3-8 years (mean time 4.76 ± 1.10). This research was carried out on panoramic radiographs and histopathological samples. Data such as gender, age, treatment methods, location of the tumor, presence of impacted teeth and its histological features were subjected to descriptive statistical analyses with the statistical software program. Results: Of the 64 analyzed cases of KCOT, 68.8% of them were men and 31.2% were females (male-to-female ratio was 2.2:1). It was observed that KCOT peaked in the third and fifth decade of life (23.4%-20.3%). The incidence of KCOT was higher in the mandible than in the maxilla (76.6%-23.4%). There was recurrence in nine out of 64 subjects (14.1%) in the follow-up period. The recurrence was more often found in posterior mandible. It is noteworthy that in 9 recurrent subjects, 7 lesions were parakeratotic and 4 lesions were associated with daughter cysts. Conclusion: Although there are several studies about KCOT in the literature, the choice of treatment modalities remains controversial. In recurrent subjects, more aggressive therapy approaches should be considered. Periodic controls and aggressive treatment approaches may be effective in the prevention of recurrences.

Odontogenic tumors: a 14-year retrospective study in Santa Catarina, Brazil

“…13,[18][19][20] We verified that the mean age of KCOT cases was 35 years, and that the posterior mandible was the most affected site. Data found in our study corroborate the data found in other studies, 13,18 and we found a greater prevalence for the male gender, in agreement with the results reported by Jing et al 19 and González-Alva et al 21 The association of KCOT with NBCCS was seen in 40% of the cases, which is very different from what was reported by González-Alva et al, 21 who only found an association of 6%. The same study reported data on the characteristics of the cases associated with NBCCS, reporting a greater prevalence in female patients (63.6%), which was different from the observations of the present study, wherein we found a higher prevalence in male patients (57% of cases associated with NBCCS).…”

Clinicopathological Evaluation of Odontogenic Tumours in Pakistan - A Seven Years Retrospective Study

“…Although cases of calcifying epithelial odontogenic tumour were reported in majority of the studies conducted on other populations (Ladeinde et al, 2005;Guerrisi et al, 2007;Gonzalez-Alva et al, 2008;Saghravanian et al, 2010) but not a single case of it was noticed in the mentioned period of our study.…”

“…It also showed predominance for males (72.9%) and a marked predilection for posterior mandible (72.9%). These on Japanese population (Gonzalez-Alva et al, 2008). Contrarily a Brazilian study by Avelar et al (2008) stated its prevalence in 3 rd and 4 th decades, dominance for females and involvement for mandibular region mainly.…”

Kératokystes des maxillaires : discordance entre les diagnostics clinique, radiologique et anatomopathologique. A propos de deux cas

“…Les kératokystes présentent un taux de récidives comparable à celui des améloblastomes. Selon certaines études, le taux de récidive peut atteindre 62 % des cas [11]. La récidive des kératokystes serait plus élevée pour la localisation mandibulaire, lorsque le kératokyste est de type parakératosique, que son aspect radiologique est multiloculaire et que l'exérèse a été réalisée en plusieurs fragments [12].…”