Keratoacanthoma Arising in Stasis Dermatitis

Abstract

A case of keratoacanthoma arising in stasis dermatitis is presented. The eczematous dermatitis was aggravated by episodes of deep tissue inflammation, yet the common course of the tumor was not altered. To our knowledge, this is the first report of a keratoacanthoma arising in stasis dermatitis.

Multiple and Relapsing Keratoacanthomas Developing at the Edge of the Skin Grafts Site after Surgery and after Radiotherapy

“…KA may appear associated with specific disorders like Muir–Torre syndrome, xeroderma pigmentosum, florid cutaneous papillomatosis, and underlying cancer, nevus sebaceous of Jadassohn. They may also be associated with other dermatoses such as stasis dermatitis, 6 thermal burns, scars, discoid lupus erythematosus, hypehrtrophic lichen planus, 7 psoriasis, and pseudoxanthoma elasticum 8 and after using chemical carcinogens like tar derivates, tobacco smoke, petroleum oil, or podophyllin. Lesions can appear after trauma: burns, 9 skin graft donor site, 4,10 puncture site, 11 or bites 9…”

Multiple keratoacanthomas arising on skin lesions of pseudoxanthoma elasticum

“…Keratoacanthomas have been observed on areas of severe atopic eczema, drug eruptions, miliaria, erythema multiforme, radiodermatitis, weather‐beaten skin, sunburn, xeroderma pigmentosum, folliculitis, stasis dermatitis, insect and tick bites, acne conglobata, lichen simplex chronicus, hypertrophic lichen planus, seborrheic dermatitis, psoriasis, discoid lupus erythematosus, nevus sebaceous of Jadassohn, linear epidermal nevus, split skin graft donor site, healing herpes zoster sites, pneumococcal and smallpox vaccination sites, nitrogen mustard patch test sites, arterial puncture for measurement of blood gases, surgical scars and thermal burns, 2–7 however, it has never before been reported as manifesting on the skin lesions of pseudoxanthoma elasticum.…”