Keloid negatively affects body image

Motoki, Thamy Harumi Cardoso; Isoldi, Felipe Contoli; Brito, Maria José de Azevedo; Gragnani, Alfredo; Ferreira, Lydia Masako

doi:10.1016/j.burns.2018.10.009

Cited by 13 publications

(12 citation statements)

References 20 publications

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“…Many members of the community lamented the visual effects of both acne and acne scarring on their physical appearance. Posters discussing scarring also tended to depict transformations using before and after pictures, recognizing improvements in self-esteem [ 14 , 15 ]. Self-confidence can also be negatively affected through what posts identify as unrealistic beauty standards in media (“it’s just a whole lot of…photoshop”) and use the forum as a mechanism to combat the pervasiveness of media representations.…”

Section: Discussionmentioning

confidence: 99%

Skincare in Social Media: Analyzing Prominent Themes in Online Dermatologic Discussions

Reddy¹

2021

Cureus

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Introduction: As the size and influence of online dermatologic communities have developed significantly in recent years, literature concerning the relationship between social media and dermatology grows more important. One community of interest is r/SkincareAddiction, a forum of over 1.2 million members on Reddit that serves as both a support group and discussion aggregator sourcing information from multiple social media platforms. Methods: This study reports on the qualitative analysis of 300 highly engaged posts to identify prominent themes in online dermatologic discussions and determine the extent of multiplatform interaction between Reddit and other dermatology-relevant social networks. Results: Results of an inductive analysis indicate discussions place an emphasis on communicating advice and improving general wellbeing, comprising 71% of measured posts. However, a large portion of this counsel lacks evidence and pseudoscientific recommendations are often accepted as factual. Additionally, 31% of entries were drawn from alternative social media sites. Conclusion: Assessing the prevalent points of discussion in dermatology-relevant communities can inform clinical practice and reveal alternative methods to advance the delivery of care. As patients increasingly seek health advice and support online, developing digital literacy in common dermatologic trends offers a unique opportunity to improve communication, disseminate evidence-based counsel, and combat misinformation in both clinical and online settings.

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Section: Discussionmentioning

confidence: 99%

Skincare in Social Media: Analyzing Prominent Themes in Online Dermatologic Discussions

Reddy¹

2021

Cureus

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“…1 These scars can cause pain and discomfort and have been associated with negative effects on social well-being, prompting physicians to seek effective treatment modalities with minimal risk of recurrence. 2 Although limited, current knowledge of keloid pathophysiology has guided first-line treatments and aided in elucidating novel therapies.…”

Section: Introductionmentioning

confidence: 99%

Multimodal Management of Facial Keloid with Tissue Expansion, Excision, and Injection of 5-FU and Triamcinolone

Marquez

Sudduth

Ormiston

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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Summary: Keloids are benign, fibroproliferative dermal growths that occur in response to injury of the skin. These hypertrophic scars can cause pain and discomfort and have been associated with negative effects on social well-being, prompting physicians to seek effective treatment modalities with minimal risk of recurrence. Although surgical excision of the keloid initially removes the scar tissue, surgery alone triggers a fibroproliferative response similar to the initial insult, resulting in a high recurrence rate. Thus, a multimodal approach may be most appropriate when surgery is indicated to limit recurrence. We present the successful treatment of recalcitrant keloid formation of the face that was treated with tissue expansion, excision, and intralesional triamcinolone and 5-flurouracil injections.

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“…1,2 Keloids have a negative influence on quality of life due to pain, itching, restriction of motion, and reduced selfesteem and negative body image. [3][4][5][6] Despite the availability of a wide variety of therapeutic options, 7 keloids are still extremely challenging to treat, with relatively low response rates to many therapies and high rates of recurrence. [8][9][10] There is a critical need for development of more effective strategies for treatment and prevention of keloids.…”

Section: Introductionmentioning

confidence: 99%

Myofibroblasts Are Not Characteristic Features of Keloid Lesions

Hahn

McFarland

Combs

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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Background: Keloids are disfiguring, scar-like lesions that are challenging to treat, with low response rates to current interventions and frequent recurrence. It has been widely reported that keloids are characterized by myofibroblasts, specialized contractile fibroblasts that express alpha-smooth muscle actin (α-SMA). However, evidence supporting a role for myofibroblasts in keloid pathology is inconclusive, with conflicting reports in the literature. This complicates development of more effective therapies, as the benefit of interventions targeting myofibroblasts is unclear. This study was undertaken to determine whether myofibroblasts can be considered characteristic of keloids. Methods: Myofibroblasts in tissue sections from keloids, hypertrophic scars (HTSs), and normal skin were localized by α-SMA immunostaining. Expression of α-SMA mRNA (ACTA2 gene) in normal skin and keloid tissue, and in fibroblasts from normal skin, keloid, and HTSs, was measured using quantitative polymerase chain reaction. Results: Normal skin did not exhibit α-SMA-expressing myofibroblasts, but myofibroblasts were identified in 50% of keloids and 60% of HTSs. No significant differences in ACTA2 expression between keloid and normal skin tissue were observed. Mean ACTA2 expression was higher in HTS (2.54-fold, P = 0.005) and keloid fibroblasts (1.75-fold, P = 0.046) versus normal fibroblasts in vitro. However, α-SMA expression in keloids in vivo was not associated with elevated ACTA2 in keloid fibroblasts in vitro. Conclusions: Despite elevated ACTA2 in cultured keloid fibroblasts, myofibroblast presence is not a consistent feature of keloids. Therefore, therapies that target myofibroblasts may not be effective for all keloids. Further research is required to define the mechanisms driving keloid formation for development of more effective therapies.

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Keloid negatively affects body image

Cited by 13 publications

References 20 publications

Skincare in Social Media: Analyzing Prominent Themes in Online Dermatologic Discussions

Skincare in Social Media: Analyzing Prominent Themes in Online Dermatologic Discussions

Multimodal Management of Facial Keloid with Tissue Expansion, Excision, and Injection of 5-FU and Triamcinolone

Myofibroblasts Are Not Characteristic Features of Keloid Lesions

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