KEBO LEAF ETHANOL EXTRACT (Euphorbia hirta L.) ANTI-INFLAMMATORY EFFECTS IN FEMALE WHITE RATS DETERMINED USING ARTIFICIAL UDEMA METHOD

Abstract

An ordinary protective reaction to tissue damage brought on by physical trauma, chemical agents, or harmful microbiological agents is inflammation. The kebo excerpt plant has significant amounts of flavonoids, which have anti-inflammatory and antioxidant properties. This study used the artificial udema method to determine the anti-inflammatory effects of Kebo Petikan leaves (Euphorbia hirta L.) ethanol extract in female white rats. This study applied a subcutaneous 1% carrageenine inducer as an anti-inflammatory drug on the soles of rats' feet. Following the injection of the test material at doses of 26 mg, 52 mg, and 104 mg, a decrease in volume was the metric that was observed. The results of the study showed the anti-inflammatory effect of ethanol extract of kebo petikan leaves at a dose of 26 mg/5ml had a strength of 32.3%, a dose of 52 mg/5ml had a strength of 78.48 %, and a dose of 104 mg/5ml had a strength of 91.46% compared to drugs.

The Test Effect of Glucose Tolerance of Green Apple (Mallus sylvestris Mill.) Juice on Male White Mice

“…In this study, the test animals used were male white mice weighing 20-40 grams using the oral glucose tolerance test method. Before the treatment, the animals were acclimated for approximately seven days to adapt the mice to their new environment (Trisna et al, 2022); the test animals fasted for 16 hours with the aim of faster absorption of the preparations. Test animals were induced to increase fasting glucose levels with 50% glucose 3g/kgBW orally, except for the normal group (Khotimah, 2016).…”

“…Testing for Decreased Blood Sugar Test animals were fasted for 16-18 hours but were still given water to drink (Trisna et al, 2022). The weight test animals were weighed, and blood sugar levels were measured in all groups.…”

EFFECT OF VARIATIONS IN HYDROLYSIS TIME ON CARBOHYDRATE LEVELS OF WHITE RICE FLOUR (Oryza sativa L.) USE OF THE SCHOORL LUFF METHOD

“…Rice plants are a type of transient crop. It only generates once and typically lasts for less than a year [1,2]. Rice is a high-carbohydrate food that provides energy.…”