“…Furthermore, two independent case-control studies have demonstrated that the KCNJ11 Glu23 is significantly overrepresented in endurance-oriented athletes compared to controls in mixed Caucasian (184 male endurance-oriented athletes with VO 2max ! 75 ml/kg/min; 61.0% vs. 50.0%; P ¼ 0.01) [108] and Spanish (98 marathon runners; 68.0% vs. 53.0%; P ¼ 0.04) [109] cohorts.…”