Current Progress in Sports Genomics

Ahmetov, Ildus I.; Fedotovskaya, Olga

doi:10.1016/bs.acc.2015.03.003

Cited by 151 publications

(188 citation statements)

References 242 publications

(314 reference statements)

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“…To date, at least 120 genetic markers have been reported to be associated with elite athlete status. 3 Because previous studies indicated that each polymorphism makes only a small contribution to the overall heritability of athlete status, simultaneous testing of multiple polymorphisms is required. 4 Williams and Folland 5 proposed a genetic algorithm, the total genotype score (TGS), to predict the genetic potential for endurance performance.…”

Section: Introductionmentioning

confidence: 99%

Lack of association between genotype score and sprint/power performance in the Japanese population

Miyamoto‐Mikami

Murakami

Tsuchie

et al. 2017

Journal of Science and Medicine in Sport

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Section: Introductionmentioning

confidence: 99%

Lack of association between genotype score and sprint/power performance in the Japanese population

Miyamoto‐Mikami

Murakami

Tsuchie

et al. 2017

Journal of Science and Medicine in Sport

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“…Especially, efficiency of the adenosine triphosphate (ATP) synthesizing resources seems to be important. In muscle tissues, the muscle isoform of creatine kinase (CKM) is a key enzyme of energy supply (2)(3)(4)(5). CK-MM is located at the surface of myosin filaments near actomyosin ATPase and is involved in the provision of the energy for the working myosin heads, supplying them with newly synthesized ATP in the course of muscle contraction (6).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Muscle-Specific Creatine Kinase (CK-MM) Gene Polymorphism (rs8111989) Among Professional, Amateur Athletes and Non-athlete Karatekas

et al. 2017

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Background: Identification of genetic markers is one of the priority trends to perform in athletes for evaluation of their efficacy. Previous studies have revealed that CK-MM may be used as a valuable marker to reflect the magnitude of skeletal muscle destruction in response to exercise. Objectives: In this study we analyzed the frequency of rs8111989CK-MM polymorphism in karatekas to find whether there is a difference among professional, amateur athletes and non-karatekas. Methods: Distribution of allele and genotype frequencies of the muscle specific creatine kinase (CK-MM) gene A/G polymorphism was assessed in a survey among 275 athletes residing in state of Isfahan (86 professional karatekas (43 male and 43 female) and 86 amateur karatekas (50 male and 36 female) and 103 non-athlete individuals (50 male and 53 female). Blood samples were taken and genotyping was performed by restriction fragment length polymorphism (RFLP) approach. Statistical analyses carried out using SPSS software and data with P < 0.05 were considered to be significant. Results: The CK-MM AG genotype frequency was significantly higher in professional and amateur karate athletes and control sub-

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“…Each of single-nucleotide polymorphisms (SNPs), usually has only a small functional effect, and therefore its original research ends with the development of genetic evaluation method, summing the number of alleles of the potential impact of SNPs for predicting athletic qualities [14,21] reactions to training [13,20] or risk of obesity, hyperlipidemia or hyperglycemia in relation to physical fitness [45]. Genetic evaluation method usually shows the distribution among Caucasian populations and although the best estimate of the athletes above, their extreme qualities cannot be reasonably explained by the summation of common SNPs with small effects [46].…”

Section: Regional Aspects Of Sports Medicinementioning

confidence: 99%

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2016

Journal of Diseases

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HAS ATHLETIC PERFORMANCE REACHED ITS PEAK?During the last two decades, sports medicine is increased and experienced a stage of rapid development, especially in such areas as the study of strength, endurance, sports injuries and psychology [1]. Athlete preparation, conditioning, including physical training, nutrition, and medicine, was affected by technological improvements and innovations in the twentieth century. In this connection, Fogel [2] coined the term "technophysiological evolution" to describe anthropometric gains of athletes' body. However, the most noticeable parameters affect the quality of sport, relate to biology, including genetics [3][4][5]: the physiological processes (especially time-dependent processes such as growth and aging [6][7][8] and environment [9,10] which can be either natural (e.g. ambient temperature, gas content, barometric pressure, winds, etc.) or artificial (human) based on the cultural [11] and technological [12] contexts.

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Current Progress in Sports Genomics

Cited by 151 publications

References 242 publications

Lack of association between genotype score and sprint/power performance in the Japanese population

Lack of association between genotype score and sprint/power performance in the Japanese population

Comparison of Muscle-Specific Creatine Kinase (CK-MM) Gene Polymorphism (rs8111989) Among Professional, Amateur Athletes and Non-athlete Karatekas

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