Kartagener's Syndrome

Md, Curtis Andrews

doi:10.1136/bmj.2.4639.1269

Cited by 15 publications

(5 citation statements)

References 1 publication

(1 reference statement)

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“…These features are well illustrated by my two cases. The first case shows the triad, whilst the second shows congenital abnormality of the paranasal sinuses to an extent which has been seen in only one previous case (Andrews, 1949). That case was later reviewed by Banham (1950), who points out that, as at birth the maxillary and mastoid antra are well-formed cavities and the frontal and sphenoidal sinuses and ethmoid air cells are underdeveloped, it would be interesting to know if this lack of development of the upper respiratory tract was always present in these cases, especially as previous writers have merely recorded absent or small frontal sinuses.…”

mentioning

confidence: 64%

Intolerance to Hexamethonium Bromide

Finnegan¹,

Trounce²

1952

BMJ

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mentioning

confidence: 64%

Intolerance to Hexamethonium Bromide

Finnegan¹,

Trounce²

1952

BMJ

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“…Consequently, about 50% of those with primary ciliary dyskinesia have situs inversus totalis. The disorder has been known as Kartagener’s syndrome 31 .…”

Section: Diagnosing the Cause Of Chronic Cough In Childrenmentioning

confidence: 99%

Diagnosis and management of chronic cough: similarities and differences between children and adults

Weinberger

Hurvitz

2020

F1000Res

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Cough is a natural process that protects the airway. Cough can occur spontaneously or voluntarily. It is considered chronic when it is present for longer than 4 weeks in children or 8 weeks in adults. In both, chronic cough causes patient distress and increased healthcare utilization. Etiologies of pediatric chronic cough include asthma, protracted bacterial bronchitis, tracheomalacia, habit cough, and various systemic disorders. While some diagnoses are identifiable by careful history alone, others require testing guided by specific pointers. Flexible fiberoptic bronchoscopy has been an important tool to identify etiologies of chronic cough that were not otherwise apparent. In adults, asthma and bronchitis are well-defined etiologies of chronic cough, but much chronic cough in adults is largely a conundrum. Reviews of adult chronic cough report that at least 40% of adults with chronic cough have no medical explanation. Gastroesophageal reflux and upper airway cough syndrome (a.k.a. post-nasal drip) have been common diagnoses of chronic cough, but those diagnoses have no support from controlled clinical trials and have been subjected to multiple published critiques. Cough hypersensitivity is considered to be an explanation for chronic cough in adults who have no other confirmed diagnosis. Gabapentin, a neuromodulator, has been associated with a modest effect in adults, as has speech pathology. While habit cough has not generally been a diagnosis in adults, there is evidence for a behavioral component in adults with chronic cough. Treatment for a specific diagnosis provides a better outcome than trials of cough suppression in the absence of a specific diagnosis. More data are needed for chronic cough in adults to examine the hypothesized cough hypersensitivity and behavioral management. This article reviews etiologies and the treatment of chronic cough in children and the conundrum of diagnosing and treating chronic cough in adults.

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“…Die Symptomkombination aus chronischer Sinusitis, Bronchiektasen und Situs inversus war bereits früher von Siewert und Kartagener als sog. Kartagener-Syndrom publiziert worden [2]. Allerdings handelte es sich hierbei um eine rein deskriptive Darstellung des Syndroms, weil es zum damaligen Zeitpunkt noch keine Hinweise auf die Ursache dieser seltenen Erkrankung gab.…”

Section: Historischer Hintergrund Und Nomenklaturunclassified

Primäre Ziliendyskinesie (PCD) – interdisziplinäre Diagnostik und Therapie

Hackenberg¹,

Scherzad²

2020

Laryngo-Rhino-Otol

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Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disease. First respiratory symptoms already occur within the first hours after birth. Major symptoms are an unexplained neonatal respiratory distress syndrome, situs inversus, persistant cough, and chronic nasal congestion, recurrent paranasal sinus disorders with or without polyps, bronchiectasis as well as male infertility. Diagnostics is complex and includes transmission electron microscopy, nasal NO assessment, high-speed video microscopy and genetic evaluations. This review gives an overview over the current diagnostic procedures and therapeutic options. The management of PCD is a multidisciplinary approach, which should be reserved to in highly specialized centers.

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Kartagener's Syndrome

Cited by 15 publications

References 1 publication

Intolerance to Hexamethonium Bromide

Intolerance to Hexamethonium Bromide

Diagnosis and management of chronic cough: similarities and differences between children and adults

Primäre Ziliendyskinesie (PCD) – interdisziplinäre Diagnostik und Therapie

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