Kaposi's Sarcoma Associated With Adult T‐cell Leukaemia

Epstein‐Barr virus infection and expression in oral lesions

“…Interestingly, HHV8 was also detected in a lymphoma that developed in a patient infected with HTLVI. KS has been previously reported in patients with HTL V I infection (Morozov et al, 1992;Ozaki et al, 1992;Srivastava et al, 1992).…”

Quantitation of human herpes virus 8 DNA in paraffin‐embedded biopsies of HIV‐associated and classical Kaposi’s sarcoma by PCR

“…HIV itself does not seem to be this causative agent 3 . Several authors reported associations between the human T‐cell lymphotropic virus type 1 and Kaposi’s sarcoma 4–9 . Recently DNA sequences of a new herpes virus, called Kaposi’s sarcoma associated herpes virus or human herpes virus 8 (HHV8), have been described in Kaposi’s sarcoma of patients infected with the acquired human immunodeficiency virus 10 .…”

Correspondence

“…With a functional similarity to HIV, HTLV-1 infection leads to immunodeficiency in the host, frequently accompanied by opportunistic infections and by the increased risk of other malignancies. A few cases of ATL-associated KS have been reported (Greenberg et al, 1990;Kamada et al, 1992;Ozaki et al, 1992), but no information is available concerning the status of HHV-8 in this type of KS that occurs in HIV-negative Japanese ATL patients.…”

“…We previously described a case of KS in a Japanese woman with ATL (Ozaki et al, 1992). HTLV-1 infection was confirmed by the presence of antibody specific for HTLV-1 and by demonstration of proviral DNA integrated in the peripheral blood lymphocytes.…”