1994
DOI: 10.1055/s-2008-1066137
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Juvenile Xanthogranuloma with Extra-Cutaneous Lesions - A Case Report

Abstract: Juvenile xanthogranuloma (JXG) is a rare affliction of early childhood comprising cutaneous and deep-seated lesions. Accurate diagnosis is important as the condition is self-limiting with spontaneous regression over a period of months. A case of congenital JXG is reported and the literature briefly reviewed.

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Cited by 12 publications
(11 citation statements)
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“…A solitary cutaneous lesion is the most common lesion but it may occur as a soft tissue lesion with or without organ involvement [1]. Juvenile xanthogranuloma has been documented in many visceral locations such as lung, bone, testis, gastrointestinal tract, kidney, heart, eye, and oral cavity [4][5][6]. It can manifest as a multisystem disease [1,7].…”
Section: Discussionmentioning
confidence: 98%
See 1 more Smart Citation
“…A solitary cutaneous lesion is the most common lesion but it may occur as a soft tissue lesion with or without organ involvement [1]. Juvenile xanthogranuloma has been documented in many visceral locations such as lung, bone, testis, gastrointestinal tract, kidney, heart, eye, and oral cavity [4][5][6]. It can manifest as a multisystem disease [1,7].…”
Section: Discussionmentioning
confidence: 98%
“…Juvenile xanthogranuloma is most often a self-limiting disease that often spontaneously regresses [1][2][3][4][5][6][7]. Conservative management of these tumors has been advocated.…”
Section: Discussionmentioning
confidence: 99%
“…Lesions can manifest before, during, or even after the diagnosis of the malignancy with some speculation that JXG may represent a neoplastic process . Lesion distribution in eyes, lungs, bones, testes, and gastrointestinal tract has been described . JXG differential diagnoses include herpes simplex virus, cytomegalovirus infection, cutaneous cryptococcosis, molluscum contagiosum, benign cephalic histiocytosis, xanthoma disseminatum, and papular xanthoma …”
Section: Discussionmentioning
confidence: 99%
“…We excluded non‐English journal articles, cases without congenital onset, cases without histopathologic confirmation, and cases of systemic JXG without cutaneous congenital JXGs. In total, we identified 31 cases of congenital JXG involving the skin only and 16 cases of congenital JXG with systemic involvement …”
Section: Methodsmentioning
confidence: 99%