“…JXG has a bimodal distribution, under 2 years and 40 years [20]. Multiple lesions are more frequent in children aged younger than 6 months [31]. Therefore, this JXG patient was rare in terms of age of onset and multiple nodules.…”
Juvenile xanthogranuloma (JXG) is a rare and benign tumor in infants. A solitary lesion on the eyelid has been reported in patients with JXG. We report a 15-year-old boy with multiple involvement of JXG on both eyelids. A mass on the left inner canthus was resected because of disturbance of the visual field and a risk of malignancy in terms of central ulceration in the lesion. The mass was examined by light microscopy. The mass had Touton giant cells with a wreath of nuclei surrounded by foamy histiocytes. No malignancy was observed. The mass showed no recurrence after resection.
“…JXG has a bimodal distribution, under 2 years and 40 years [20]. Multiple lesions are more frequent in children aged younger than 6 months [31]. Therefore, this JXG patient was rare in terms of age of onset and multiple nodules.…”
Juvenile xanthogranuloma (JXG) is a rare and benign tumor in infants. A solitary lesion on the eyelid has been reported in patients with JXG. We report a 15-year-old boy with multiple involvement of JXG on both eyelids. A mass on the left inner canthus was resected because of disturbance of the visual field and a risk of malignancy in terms of central ulceration in the lesion. The mass was examined by light microscopy. The mass had Touton giant cells with a wreath of nuclei surrounded by foamy histiocytes. No malignancy was observed. The mass showed no recurrence after resection.
“…2 Lezyonlar en sık baş boyun ve üst gövdede yerleş-mektedir. Hastaların %40-70'i hayatın ilk bir yılında ortaya çıkmata çocukluk döneminde erkeklerde daha sık iken, erişkinlerde her iki cinsiyette eşit oranda görülmektedir.…”
Section: Olguunclassified
“…Literatürde nörofibro-matoz Tip 1, juvenil miyelomonositik lösemi, ürti-kerya pigmentosa, Niemann-Pick ve diabetes mellitus ile birliktelik bildirilmiştir. 2,4 Tanı genellikle klinik görünüm destekli histopatolojik inceleme ile konulmaktadır. Histopatolojik incelemede sitoplazması vakuollü histiyositler (köpüksü hücreler) ve çelenk görünümünde periferde köpüksü dejenerasyon santralde homojen eozinofilik sitoplazma içeren Touton dev hücrelerinin varlığı ksantogranülom için karakteristiktir.…”
A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Ksantogranülom, juvenil; histiyositoz K Ke ey yw wo or rd ds s: : Xanthogranuloma, juvenile; histiocytosis Cop yright
“…C'est une lésion cutanée bénigne du nourrisson et du jeune enfant. Dans 1/5 des cas les lésions sont présentes à la naissance et dans 4/5 des cas avant l'âge de 1 an [1]. Des rares cas ont été décrits chez l'adolescent et même chez l'adulte [2].…”
Section: Commentairesunclassified
“…Rarement le xanthogranulome peut intéresser les muqueuses (lèvre, langue, palais, gencive) [2][3][4]. Des localisations extracutanées ont été également décrites dans la littérature réalisant la xanthogranulomatose systémique [1]. L'association à une neurofibromatose est possible [5].…”
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