Juvenile Myoclonic Epilepsy: A Focus on the Efficacy of Therapy and the Rate of Relapses According to Long-Term Follow-Up Data

Юношеская миоклоническая эпилепсия (ЮМЭ) представляет собой форму идиопатической (генетической) генерализованной эпилепсии (ИГЭ), диагностика которой основана на строгих клинических и электроэнцефалогра-фических (ЭЭГ-) критериях, предложенных Международ-ной противоэпилептической лигой (ILAE). В основу ее дифференциации положены тип и возраст дебюта присту-пов [1].По данным эпидемиологических исследований, в раз-ных странах частота встречаемости ЮМЭ варьирует от 9,6 до 41% среди ИГЭ и от 1,07 до 10,2% среди всех форм эпи-лепсии. Точную частоту встречаемости ЮМЭ трудно оце-нить в связи с тем, что ее диагностика часто запаздывает, диагноз устанавливается ретроспективно, чаще при разви-тии первого генерализованного тонико-клонического при-падка (ГТКП

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Juvenile myoclonic epilepsy: neurophysiological aspects

Шилкина

Шнайдер

Дмитренко

et al. 2018

RJTAO

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Problems of juvenile myoclonic epilepsy. A view through the prism of time

Карлов

Zolovkina

2017

Z. nevrol. psikhiatr. im. S.S. Korsakova

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The authors present a comparative analysis of the results of the study of 72 adolescent patients with juvenile myoclonic epilepsy (JME), which were published in 2010, and a new sample of patients over the last 5 years with the publications of domestic and foreign authors. Difficult clinical cases are described. These data indicate positive shifts in the diagnosis and treatment of JME. However, the question of diagnosis is still a hard problem for neurologists. The questions to be resolved are: gender aspect of the disease, to what extent levetiracetam could be a drug of first choice and to what extent valproats could be replaced; monitoring of children born to mothers with JME, a role of paternal inheritance.

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The effectiveness of antiepileptic therapy in patients with epileptic syndromes associated with myoclonic seizures

Миронов

Чебаненко

Бурд

et al. 2020

Z. nevrol. psikhiatr. im. S.S. Korsakova

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Juvenile Myoclonic Epilepsy: A Focus on the Efficacy of Therapy and the Rate of Relapses According to Long-Term Follow-Up Data

Cited by 5 publications

References 17 publications

Juvenile myoclonic epilepsy: neurophysiological aspects

Juvenile myoclonic epilepsy: neurophysiological aspects

Problems of juvenile myoclonic epilepsy. A view through the prism of time

The effectiveness of antiepileptic therapy in patients with epileptic syndromes associated with myoclonic seizures

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