Jussara (<i>Euterpe edulis</i>Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by<i>trans</i>-Fatty Acids in the Colon of Offspring

Morais, Carina Almeida; Oyama, Lila Missae; Oliveira, Juliana Lopez de; Garcia, Márcia Teixeira; Rosso, Veridiana Vera de; Amigo, Laís Sousa Mendes; Nascimento, Cláudia Maria Oller do; Pisani, Luciana Pellegrini

doi:10.1155/2014/987927

Cited by 30 publications

(19 citation statements)

References 71 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous data by our research group using a metabolic programming model revealed that supplementing the diet of pregnant rats with juçara berries (262.4 mg ACN/100 g fresh matter) reduced metabolic and inflammatory markers and increased Lactobacillus and Bifidobacterium spp. expression of genomic DNA and ZO‐1 gene in their offspring, demonstrating that phenolic compounds present in this fruit contribute to the control of inflammation and prevention of the development of chronic diseases through the intestinal pathway up until adulthood .…”

Section: Anthocyanins and Gut Microbiota Modulationmentioning

confidence: 99%

Contribution of anthocyanin‐rich foods in obesity control through gut microbiota interactions

2017

Self Cite

View full text Add to dashboard Cite

Obesity is characterized by low-grade inflammation and a number of metabolic disorders. Distal gut microbes' content (microbiota) is not yet fully understood but evidence shows that it is influenced by internal and external factors that modulate its composition and function. The evidence that gut microbiota composition can differ between healthy and obese individuals, as well as for those who maintain specific dietary habits, has led to the study of this environmental factor as a key link between the pathophysiology of obesity and gut microbiota. Data obtained about the role of anthocyanins (ACNs) in microbiota may lead to different strategies to manipulate bacterial populations and promote health. Anthocyanins have been identified as modulators of gut microbiota that contribute to obesity control and these bioactive compounds should be considered to have a prebiotic action. This review addresses the relevance of knowledge about the influence of anthocyanins-rich food consumption on microbiota, and their health-promoting potential in the pathophysiology of obesity. © 2017 BioFactors, 43(4):507-516, 2017.

show abstract

Section: Anthocyanins and Gut Microbiota Modulationmentioning

confidence: 99%

Contribution of anthocyanin‐rich foods in obesity control through gut microbiota interactions

2017

Self Cite

View full text Add to dashboard Cite

show abstract

“…Studies in our group showed that jussara, besides the colorant power provided by the anthocyanins, is accounted for in several beneficial results from a perspective of health and well-being [27,[30][31][32]. Jussara pulp has been recognized as a superfood due to its composition, mainly, for the high concentration of anthocyanins and other phenolic compounds; in fact, these bioactive compounds are considered an attractive source of pigments and also means to ward off several diseases [27,33,34]. In this context, the pulp as a whole can be used in food preparations to confer color and beneficial biological effects.…”

Section: Introductionmentioning

confidence: 99%

Development and Characterization of Electrospun Nanostructures Using Polyethylene Oxide: Potential Means for Incorporation of Bioactive Compounds

Ramos

Giaconia

Marco

et al. 2020

Colloids and Interfaces

View full text Add to dashboard Cite

The development of processes for stabilization of the properties of bioactive compounds has been studied in recent years, and the use of nanotechnology is among the most discussed routes. The present work addressed the assembly of nanostructures using polyethylene oxide (PEO), the production of core-shell nanofibers (NFs) with bioactive compounds, and the evaluation of their microscopic and physical characteristics. Aqueous solutions of PEO were electrospun by varying different process and solution parameters (PEO and NaCl concentrations, feeding rate, the tip-to-collector distance (TCD), and applied voltage) in order to optimize production of nanostructures. The best condition obtained was evaluated to form core-shell NFs composed by jussara pulp as a source of anthocyanins. To assess the production of NFs with PEO and jussara pulp, feed solutions were prepared in acetate buffer (pH 4.5) with 6% PEO and 10% lyophilized jussara pulp, at a feeding rate of 150 μL·h−1 and TCD of 15 cm using an applied voltage of 10 kV to form core-shell NFs. The results revealed the formation of core-shell NFs with a diameter of 126.5 ± 50.0 nm. The outcomes achieved represent a crucial step in the application of anthocyanins in food systems as pigments, establishing a basis for further research on the incorporation of nanomaterials into foodstuff.

show abstract

“…In animals, juçara exerted a beneficial effect in the offspring of mothers who consumed the fruit in the perinatal period. There was an improvement in the lipid profile, glucose concentration, body composition, and intestinal microbiota and a reduction in low-grade inflammation in the colon of 21-day-old puppies [ 20 ]. In contrast, supplementation with 2 % juçara of the diet of ApoE − / − mice for 12 weeks did not affect hepatic oxidation or the inflammatory profile of these animals [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Juçara pulp supplementation improves glucose tolerance in mice

Oyama

Silva

Carnier

et al. 2016

Diabetol Metab Syndr

View full text Add to dashboard Cite

BackgroundThe consumption of hyperlipidic and hypercaloric diet is considered a major factor to promote obesity and the consumption of food with antioxidant properties, like Juçara (Euterpe edulis Mart), could be a tool to prevent the deleterious effect of high white adipose deposition. The aim of the present study was to evaluate the effect of administration of juçara pulp in mice fed a high-fat, high-calorie diet on glucose tolerance and adipose tissue inflammatory status.MethodsMice were distributed into the following groups: control diet; control diet plus 0.5 % of juçara; control diet plus 2 % of juçara; hypercaloric and hyperlipidic diet; hypercaloric and hyperlipidic diet plus 0.5 % of juçara and hypercaloric and hyperlipidic diet plus 2 % of juçara. Treatments started when mice were 8 weeks old and carried on for a total period of 10 weeks. The serum glucose, triacylglycerol, total cholesterol, insulin, adiponectin, lipopolysaccharides and free fatty acids concentrations were measured. Oral glucose tolerance test was performed. TNF-α, IL-6, and IL-10 protein level were determined by ELISA on mesenteric and epididymal white adipose tissues. Determination of catalase activity was realized in the same tissues. Data were analysed using one-way analysis of variance and post hoc analysis was performed with the Tukey’s test.ResultsThe addition of 0.5 % juçara improved glycemic response in animals that consumed normocaloric as well as hypercaloric and hyperlipidic diets (HC). Supplementation with 0.5 and 2 % did not change the body composition of animals that received the HC diet; however, the animals fed the normocaloric diet with 2 % juçara gained body mass. An intake of 2 % juçara in the HC diet promoted a reduction of catalase activity and IL-10 level in epididymal adipose tissue.ConclusionsThese results suggest that with the administration of 0.5 % juçara, the beneficial effects of polyphenols overcome the deleterious effects of macronutrient composition of juçara, whereas with the administration of 2 % juçara promotes damage by the composition of the fruit and overshadows the beneficial effects of polyphenols on glucose metabolism. On the other hand, higher juçara supplementation improves the inflammatory status targeted by the HC diet.

show abstract

Jussara (Euterpe edulisMart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced bytrans-Fatty Acids in the Colon of Offspring

Cited by 30 publications

References 71 publications

Contribution of anthocyanin‐rich foods in obesity control through gut microbiota interactions

Contribution of anthocyanin‐rich foods in obesity control through gut microbiota interactions

Development and Characterization of Electrospun Nanostructures Using Polyethylene Oxide: Potential Means for Incorporation of Bioactive Compounds

Juçara pulp supplementation improves glucose tolerance in mice

Contact Info

Product

Resources

About